J. Allday, "The transcriptional co-repressor C- terminal Binding Protein (CtBP) associates with centrosomes during mitosis," Cell Cycle, vol. 5, no. 5, pp. 530-537, 2006.Spyer M,Allday MJ.The transcriptional co-repressor C-terminal binding protein (CtBP) associates with centrosomes ...
A protein binding to CArG box motifs and to single-stranded DNA functions as a transcriptional repressor Author links open overlay panelShinji Kamada, Takeshi MiwaShow more Add to Mendeley Share Cite https://doi.org/10.1016/0378-1119(92)90276-UGet rights and content Abstract A CArG box motif ...
TATA binding protein (TBP) served as a loading control. (d) qPCR analysis of Cxcl1 mRNA expression in WT and Hes1 KO BMDMs stimulated with Pam3Cys (10 ng/ml) or R848 (1 μg/ml) for 3 h. Representative data is shown as means ± s.d. of technical triplicate determinants from two...
Figure 5. PARP protein is a transcriptional repressor.A, PARP promoter transcriptional activity in wild type (PARP+/+) and PARP−/− fibroblasts.B, expression of human PARP or its DNA-binding domain down-regulates promoter activity. PARP−/− cells were co-transfected with pPR-PARP and...
Despite unequivocal roles in disease, transcription factors (TFs) remain largely untapped as pharmacologic targets due to the challenges in targeting protein–protein and protein–DNA interactions. Here we report a chemical strategy to generate modular synthetic transcriptional repressors (STRs) derived fr...
英文名称:Recombinant Human Transcriptional Repressor Protein YY1 Protein(C-6His)纯度:> 99%包装信息:50ug/RMB 1950;100ug/RMB 2890;200ug/RMB 3760备注:Transcriptional repressor protein YY1;Delta transcription factor;INO80 complex subunit S;NF-E1;Yin a电话...
Mitogen-activated protein kinase (MAPK/MPK) cascades function upstream to regulate CBFs. However, the mechanism by which MPKs control CBF expression during cold stress signaling remains unknown. This study showed that the activity of MYB15, a transcriptional repressor of cold signaling, is regulated...
A major subfamily of those proteins, the Krüppel-associated box (KRAB) domain-containing Cys2His2-zinc finger proteins, have been described as potent transcriptional repressors. So far, however, no DNA-binding sites for KRAB domain-containing zinc finger proteins have been isolated. Using a ...
Protein A/G magnetic beads. RNAs were extracted using RNAeasy kit (Qiagen) with DNAse treatment, and mRNA levels were measured by qRT-PCR using the primers listed below. Binding to the target RNA was calculated as a percent of the input using fold enrichment methods. YBX1 binding to ...
transcription. These include the promoter, plus response elements, activator and enhancer sequences for binding of transcription factors to aid RNA polymerase binding and promote expression, and operator or silencer sequences to which repressor proteins bind to block RNA polymerase attachment and prevent...