注意,文献中经常把结合位点和结合域混淆(binding site ,binding motif) 我们推荐保留“site”这个词来定义某一特别sequence(基因的或artificial),这是一个factor结合的地方。而“motif”这个词进行结合特异性的genetic(遗传学的)描述,通过汇总一系列sites的信息进行汇总得到。 定义:TFBM (transcription factor binding mo...
网络转录因子结合位点 网络释义 1. 转录因子结合位点 鉴定调控序列的转录因子结合位点(Transcription Factor Binding Sites)。预测“转录因子-靶基因”转录调控关系,在此基础上 … www.biosino.com.cn|基于6个网页 例句 释义: 全部,转录因子结合位点
Second, the phrase may mean a collection of DNA sequences that conform to a common pattern (motif) and are specifically recognized by a common transcription factor. As individual binding sites for a given transcription factor are often very different, a motif is usually represented by a ...
To address these challenges, we propose TBiNet, an attention based interpretable deep neural network for predicting transcription factor binding sites. Using the attention mechanism, our method is able to assign more importance on the actual TF binding sites in the input DNA sequence. TBiNet ...
gtrdadatabaseoftranscriptionfactorbindingsitesidentifiedby 系统标签: gtrdseqchip点识别transcriptionbinding NucleicAcidsResearch,20161doi:10.1093/nar/gkw951GTRD:adatabaseoftranscriptionfactorbindingsitesidentifiedbyChIP-seqexperimentsIvanYevshin1,2,RuslanSharipov1,2,3,TagirValeev1,4,AlexanderKel1,5andFedorKolp...
Transcription factor binding sites (TFBS) in gene promoter regions are often predicted by using position specific scoring matrices (PSSMs), which summarize... DT Holloway,M Kon,C Delisi - 《Genome Informatics International Conference on Genome Informatics》 被引量: 102发表: 2004年 Multiple non-col...
Some of the “missing” overlap could perhaps be explained by alternative transcription factor binding sites, where a binding site active in only one cell type could have another nearby site active in the other cell type. To test this possibility, we counted the number of overlaps when allowing...
A sequence motif is a short recurring pattern with biological significance such as a DNA-recognition sequence for a transcription factor (TF), an mRNA splicing signal, or a functional region of a protein domain. Many high-throughput experimental approaches and computational tools have been developed...
Transcription factors (TFs) form complexes that bind regulatory modules (RMs) within DNA, to control specific sets of genes. Some transcription factor binding sites (TFBSs) near the transcription start site (TSS) display tight positional preferences relative to the TSS. Furthermore, near the TSS,...
Studies of gene regulation often utilize genome-wide predictions of transcription factor (TF) binding sites. Most existing prediction methods are based on sequence information alone, ignoring biological contexts such as developmental stages and tissue ty