定义:transcription factor binding site(TFBS) TFBS指的是TF特异结合的DNA分子的position(位置),延伸的话,就是DNA片段的序列边界。 注意,文献中经常把结合位点和结合域混淆(binding site ,binding motif) 我们推荐保留“site”这个词来定义某一特别sequence(基因的或artificial),这是一个factor结合的地方。而“motif”...
Transcription factor binding sitesConvolutional neural networksMotif discoveryBioinformaticsAutoencoderTranscription factor binding site (TFBS) is a DNA sequence that binds to transcription factor and regulates the transcription process of the gene. Although deep learning algorithms are superior to traditional ...
7] and various pattern-matching tools have been developed for this purpose. These tools fall into two classes: those that predict clusters of transcription factor binding sites or those that predict
to control specific sets of genes. Some transcription factor binding sites (TFBSs) near the transcription start site (TSS) display tight positional preferences relative to the TSS. Furthermore, near the TSS, RMs can co-localize TFBSs with each other and the TSS. The proportion of TFBS positio...
Gene expression is to large degree regulated by the specific binding of protein transcription factors to cis-regulatory transcription factor binding sites in gene promoter regions. Despite the identification of hundreds of binding site sequence motifs, t
TSS: Transcription start site TF: Transcription factor TFBS: Transcription factor binding site RDM: Remote dependency model PWM: Position weight matrix SCCM/E: Spearman correlation coefficient between methylation and expression profiles CGI: CpG island DIC: Discrete information content.References...
TF: Transcription factors TFBS: Transcription factor binding sites References Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65:87–108. Article PubMed Google Scholar Favoriti P, Carbone G, Greco M, Pirozzi ...
The control of the expression of the early ORFs in PVs depends on the binding of cellular and viral transcription factors to the upstream regulatory region (URR) of the virus. It is believed that there is a core of transcription factor binding sites (TFBS) common to all PVs, with ...
version 1.31.2 Sep 11, 2021 1bda142·Sep 11, 2021 History 327 Commits R data inst man src tests vignettes .Rbuildignore .gitignore DESCRIPTION NAMESPACE NEWS README.md TFBSTools.Rproj README TFBSTools Software Package for Transcription Factor Binding Site (TFBS) Analysis ...
Transcriptional factor (TF)-encoding genes have been recognized as one important source of the diversity and change that underlie the evolution of plants6,7. Moreover, identification of the transcriptional factors (TF;transelements) and their cognate transcriptional factor binding-sites (TFBS;ciselement...