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The tumour stroma responds to anticancer therapies by inducing therapeutic resistance, which can ultimately lead to fatal disease. Anticancer therapies should target both cancer cells and the stromal compartment to be effective and result in improved patient outcomes. This is a preview of subscription ...
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As the Orioles continue their rebuild, the team is in position to take stock of what it has in-house. Anthony Santander emerged as a power threat in the early part of this season, leading the team with 11 homers before he went down because of an oblique injury, but the team has also...
https://treasury.gov.au/coronavirus. Zhong, D. (2020). Respond calmly and move forward-China’s economy responds to the impact of the new crown pneumonia epidemic. Economic Daily. http://www.gov.cn/xinwen/2020-07/27/content_5530242.htm. Download references...
What was originally called “osteoclast activating factor” associated with these lytic lesions has since been characterised as interleukin (IL)-1, IL-6, and TNF alpha plus RANKL [36]; all cytokines very familiar to rheumatologists. If plasma cells are directly or indirectly responsible for the ...
albicans, Aspergillus spp, Cryptococcus spp, Blastomyces spp, Paracoccidioides brasiliensis and Sporothrix spp [201], however, there is no clear idea about what type of effector and memory response would provide a long-term protective immune response in the host. 4.2.2. Humoral immune response ...
What structural and functional properties does the lineage composition confer each compartment? In order to address this question, we examined the connectivity and projection biases across the large-field neurons and their upstream partners in lateral neuropils. We started with the EB, the compartment...
It remains unclear that whether TMB status is correlated with the prognosis of NSCLC patients to the traditional treatments, and what is the prognostic power of the combination of TMB with other biomarkers. Here, we aim to determine whether TMB status, and/or in combination with PD-L1 ...
For example, if you eat something irritating or toxic, your gut responds by producing more serotonin. The extra dose moves the unwanted food along, expelling it from your body more quickly. The response is also why increased levels of serotonin can make you nauseated, and why drugs that targ...