EphB2, TNF-alpha, TNFR2, NF-kappaB, NeuroregenerationHIV-1 infected individuals are at high risk of developing HIV-associated neurocognitive disorders (HAND) as HIV infection leads to neuronal injury and synaptic loss in the central nervous system (CNS). The neurotoxic effects of HIV-1 are ...
Association of TNF-alpha and TNFR1 promoters and 30 UTR region of TNFR2 gene polymorphisms with genetic susceptibility to tobacco-related oral carcinoma in Asian Indians. Oral Oncol 2008;44:455-63.Gupta R, Sharma SC, Das SN. Association of TNF‐alpha and TNFR1 ...
Conversely, TNFR2, which does not possess an intracellular death domain, triggers cell survival and proliferation [25]. In the synovium of active RA patients, both TNF-α receptors are upregulated, at the protein and mRNA levels [26]. In addition, in peripheral blood mononuclear cells (PBMC...
Cui YH, LeY Zhang X, Gong W, Abe K, Sun R, Van Damme J, Proost P, Wang JM (2002) Up-regulation of FPR2, a chemotactic receptor for amyloid beta 1-42 (A beta 42), in murine microglial cells by TNF alpha. Neurobiol Dis 10(3):366–377...
TNF-alpha is a major proinflammatory cytokine. sTNFR2 is the soluble form of one of its receptors and is strongly expressed on stimulated lymphocytes. To further understand the role of TNF-alpha, sTNFR2 and other cytokines in the pathogenesis in HPV-related neoplasia, the profiles of serum ...
TNF-alpha: an activator of CD4+FoxP3+TNFR2+ regulatory T cells . Curr Dir Autoimmun (2010) 11 :119–34.10.1159/000289201 [ Cross Ref ]Chen X., Oppenheim J.J. TNF-alpha: An activator of CD4+FoxP3+TNFR2+ regulatory T cells. Curr. Dir. Autoimmun. 2010; 11 :119–134. doi: ...
7-OMe-APBT透過活化caspase-8/mitochondria的死亡路徑引發細胞凋亡,進一步活化p38 MAPK致使TNF-α及TNFR2表現增加; p38 MAPK誘導c-Jun磷酸化導致TNFR2 promoter活性增加,預先處理p38 MAPK抑制劑 (SB202190)能抑制7-OMe-APBT上調TNFR2 promoter冷光活性及mRNA表現的效應;另一方面,7-OMe-APBT透過PP2Acα介導TTP的...
The role of IL-6, IL-10, TNF-alpha and its receptors TNFR1 and TNFR2 in the local regulatory system of normal and impaired human spermatogenesis. Bialas M,Fiszer D,Rozwadowska N,Kosicki W,Jedrzejczak P, et al. American Journal of Reproductive Immunology . 2009...
A number of studies reported associations of HLA-DRB1, TNFalpha (TNF) promoter and TNF receptor II (TNFR2, TNFRSF1B) polymorphisms with systemic lupus erythematosus (SLE), however, the results have often been inconsistent. Such lack of consistency could partly derive from the population ...
(2011). TNFα-induced IP3R1 expression through TNFR1/PC-PLC/PKCα and TNFR2 signalling pathways in human mesangial cell. Nephrol. Dial. Transplant. 26, 75-83. doi: 10.1093/ndt/gfq406Wang YR, Li ZG, Fu JL, Wang ZH, Wen Y & Liu P (2011). TNFalpha-induced IP3R1 expression through...