产品活性:肿瘤坏死因子 α (TNF alpha) 是一种有效的促炎细胞因子。TNF alpha 与其受体结合,主要是 TNFR1 和 TNFR2,然后传递信号以实现炎症和细胞死亡等生物学功能。TNF alpha 通过 TNFR2 受体激活 NF-κB 通路促进癌细胞生长、侵袭和转移,但抗 TNF-α 抗体能显着抑制结肠炎相关癌症 (CAC) 小鼠的肿瘤发展。
TNF-alpha-308 G allele was significantly lower (Pc=0.004; OR=3.85), whereas A allele was significantly higher (Pc=0.004; OR=0.25) in patients compared with controls. No significant change was observed at -238 promoter site between the two groups. In the case of TNF receptors, both TNFR1...
上海玉博生物科技有限公司做为cisbio代理商之产品64BDTNFPEG-Human TNFalpha/TNFR1 binding kit的产品销售公司,专业经营原装进口抗体(单克隆、多克隆)、重组蛋白、检测试剂盒、标准品、细胞因子、胎牛血清、细胞培养类等生物试剂以及耗材。 玉博生物致力于成为科研试剂采购一体化解决方案提供商! 1,货品多且全,目前,...
Superoxide anion-induced pain and inflammation depends on TNFα/TNFR1 signaling in mice cita-Borin FY, Zarpelon AC, Pinho-Ribeiro FA et al (2015) Superoxide anion-induced pain and inflammation depends on TNFalpha/TNFR1 signaling in mice... ...
All hearts with low over-expression of TNFα, independent of human or murine origin, have improved contractile performance and increased Ca 2+ sensitivity (by 0.2–0.26 pCa). Hearts lacking TNFR1 have contractile performance equal to wild type hearts. Recovery from ischemia was greater in TIA-1...
Lozano J M,Collado J A,Medina T,et al.Protection against liver injury by PGE1or anti-TNF-alpha is associated with a reduction of TNF-R1expression in hepatocytes. Scandinavian Journal of Gastroenterology . 2003Lozano JM,Collado JA,Medina T,et al.Protection against liver injury by PGE1 of anti...
involving the execution phase of apoptosis and inhibition of TNFR1/IKB alpha/p65 signaling. Therefore, small molecules such as PNU-74654 may identify potential new treatment strategies for TC. Keywords: PNU-74654;TNF receptor-1;apoptosis;testicular cancer...
However, anti-TNF-alpha-induced cutaneous side effects have been increasingly reported in the literature... FJ Melo,S Magina - 《International Journal of Dermatology》 被引量: 0发表: 2018年 B Lymphocytes in Rheumatoid Arthritis and the Effects of Anti TNF-alpha Agents on B Lymphocytes: A ...
产品活性:肿瘤坏死因子 α (TNF alpha) 是一种有效的促炎细胞因子。TNF alpha 与其受体结合,主要是 TNFR1 和 TNFR2,然后传递信号以实现炎症和细胞死亡等生物学功能。TNF alpha 通过 TNFR2 受体激活 NF-κB 通路促进癌细胞生长、侵袭和转移,但抗 TNF-α 抗体能显着抑制结肠炎相关癌症 (CAC) 小鼠的肿瘤发展。
产品活性:肿瘤坏死因子 α (TNF alpha) 是一种有效的促炎细胞因子。TNF alpha 与其受体结合,主要是 TNFR1 和 TNFR2,然后传递信号以实现炎症和细胞死亡等生物学功能。TNF alpha 通过 TNFR2 受体激活 NF-κB 通路促进癌细胞生长、侵袭和转移,但抗 TNF-α 抗体能显着抑制结肠炎相关癌症 (CAC) 小鼠的肿瘤发展。