因此,TNFa、IL-1与NF-kB之间造成细胞因子网络中的恶性循环.TNF-α作为一种重要的肝脏炎症介质是肯定的, TNF-α对肝纤维化形成的作用可能是间接的,是通过刺激肝脏炎症而发挥促纤维化作用.(!!!现在的网怎么了,有时写好的东东发了却要重新登陆,结果原来的写好的东东没了,又要重写,真是打击积极性!!!) 有用(...
1.Aeschlimann FA, Batu ED, Canna SW, Go E, Gul A, Hoffmann P, et al. A20 haploinsufficiency (HA20): clinical phenotypes and disease course of patients with a newly recognised NF-kB-mediated autoinflammatory disease. Ann Rheum Dis. 2018;77(5):728-35. 2.Duncan CJA, Dinnigan E, Theob...
1.Aeschlimann FA, Batu ED, Canna SW, Go E, Gul A, Hoffmann P, et al. A20 haploinsufficiency (HA20): clinical phenotypes and disease course of patients with a newly recognised NF-kB-mediated autoinflammatory disease. Ann Rheum Dis. 2018;77(5):728-35. 2.Duncan CJA, Dinnigan E, Theob...
NF-kB target microRNAs and their target genes in TNFa-stimulated HeLa cells. Biochim Biophys Acta BBA Gene Regul Mech 2014;1839(4):344e54.Zhou F, Wang W, Xing Y, Wang T, Xu X, Wang J, et al. NF-kappaB target microRNAs and their target genes in TNFalpha-stimulated HeLa cells. ...
产品名称:NFKBTHP1TNFA INHIBITOR PROFILI .0订购此产品 供应商:Invitrogen 规格:1 EACH 目录价:1.23 库存状态: CAS编号: 应用范围: 种属来源: 相关信息: 保存条件: 说明书地址:点击查看详细 打印此页关闭此页 上一个:NFKBTHP1TNFA ACTIVATOR PROFILI[PCP5249/1 EACH] ...
Identification of NF-kB-regulated genes induced by TNFa utilizing expression profiling and RNA interference. Zhou A,Scoggin S,Gaynor RB, et al. Oncegene . 2003Zhou A, Scoggin S, Gaynor RB, Williams NS: Identifi- cation of NF-kB-regulated genes induced by TNFa util- izing expression ...
Also, LDN193189 inhibited the ID1 response to TNFa in dPASMCs without affecting the IL8 response, confirming the ID1 response is indirectly via BMP receptors and not via canonical NF-kB signalling (Supplementary Fig. 9c,d). Collectively, these data demonstrate that TNFa reduces BMPR2 and BMP2...
as inflammation, immunity, development, cell proliferation and apoptosis by controlling the expression of NF-kB-dependent survival factors, cytokines and proinflammatory molecules.1–3 In its resting state, NF-kB exists in a stable cytosolic complex with a member of the inhibitor kB (IkB) family....
百度试题 题目死亡受体(如I型TNFa受体)介导细胞凋亡主要通过激活() A. 蛋白激酶A(PKA) B. Ca2+/钙调素依赖性蛋白激酶 C. 蛋白激酶C(PKC) D. NF-kB E. caspases 相关知识点: 试题来源: 解析 A.蛋白激酶A(PKA) 反馈 收藏
浓度:1000 μg/ml 库存:现货 Size 点击咨询在线客服 TNFAIP3, also named A20, is a cytoplasmic zinc finger protein that inhibits nuclear factor kappa-B (NFKB) activity and tumor necrosis factor (TNF)-mediated programmed cell death. A20 is a ubiquitin-editing enzyme that contains both ubiquitin ...