(1995). A synergistic relationship between TNF-alpha, IL-1 beta, and TGF-beta 1 on IL-6 secretion by the IEC-6 intestinal epithelial cell line. Immunology, 86, 6 ± 11.McGee D, Bamberg T, Vitkus S, McGhee J. A synergistic relationship between TNF-alpha, IL-1 beta, and TGF-beta ...
白细胞介素-1B(IL-1B)是促炎细胞因子和急性期反应诱导剂。在微生物诱导后,IL-1B主要由单核细胞,巨噬细胞和树突细胞产生。肿瘤坏死因子-a(TNF-a)由许多不同细胞类型产生,例如 单核细胞,巨噬细胞,T细胞和B细胞。在TNF-a的许多作用中,有针对细菌感染,细胞生长调节,免疫系统调节和参与败血症性休克的保护。
Induction by lipopolysaccharide, IFN-gamma, and IL-1 beta. Astrocytes have the capacity to secrete or respond to a variety of cytokines including IL-1, IL-6, IL-3, and TNF-alpha. In this study, we have examined the capacity of astrocytes to secrete TNF-alpha in response to a variety ...
Background: IL-113 and TNF-alpha have been demonstrated as pro-inflammatory cytokines to participate in the innate immune response and suppression of HBV infection. However, the exact relationship between IL-1 beta, TNF-alpha gene polymorphisms and HBV infection remains unknown. Our study aims to...
In the general population, depression is a common mental health disorder worldwide, with a prevalence rate of around 5% among adults [1]. In depressed people, several cytokines such as TNF-α, IL-1β, IL-6, IL-10, IL-12, IL-13, and IL-18 were found to be elevated, and IFN-γ ...
Modulation of TNF-alpha and IL-1beta in human PBMC and monocytes by para-Phenylenediamine and its autoxidation productM. HamidizadehS. BreuerHans MerkBrunhilde Blömeke
Toxicology Modulation of TNF-alpha-mediated acute lung inflammation| A role for IL-1beta and soluble TNF receptors UNIVERSITY OF ROCHESTER Jacob N. Finkelstein SapersteinSara CTumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) are key mediators of numerous lung inflammatory diseases....
Finally, at a ratio of approximately 1:1 to 1:25, sTNFR1:sTNFR2 functioned as TNF-alpha antagonists in vitro . Taken together, the studies in this thesis suggest that IL-1beta modulates TNF-alpha-mediated inflammatory lung diseases by altering TNF receptor shedding and expression in ...
TNF-alphaIL-6IL-1betaPolymorphismMeta-analysisBackground Several studies on the association of TNF-alpha (−308 G/A), IL-6 (−174 G/C) and IL-1beta (−511 C/T) polymorphisms with polycystic ovary syndrome (PCOS) risk have reported conflicting results. The aim of the present ...
Induction of nuclear factor-κB and its downstream genes by TNF-α and IL-1β has a pro-apoptotic role in pancreatic beta cells[J] . Diabetologia . 2008 (7)Ortis F, Naamane N, Kreins AY, Rasschaert J, Moore F, Theatre E, et al. Induction of Nuclear Factor-κB and its Downstream...