The TNF-|[alpha]||[sol]|NF-|[kappa]|B signaling pathway has a key role in methamphetamine|[ndash]|induced blood|[ndash]|brain barrier dysfunctionJournal of Cerebral Blood Flow & Metabolism stands at the interface between basic and clinical neurovascular research, and features research on ...
In the current study, we explored the signaling pathways responsible for DADS suppressive effect on TNFα mediated CCL2 release using PCR Arrays, RT-PCR and western blots. The data in this study show that TNFα initiates a rise in NFκB mRNA, which is not reversed by DADS. However, TNF...
Signaling pathway via TNF-α/NF-κB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis Signaling pathway via TNF-α/NF-κB in intestinal epithelial cells may be directly involved in colitis-associated carcino-genesis. Am J Physiol Gastrointest......
[11] Ohtake F,Saeki Y,Ishido S,et al.The K48-K63Branched Ubiquitin Chain Regulates NF-κB Signaling[J].Mol Cell,2016,64(2):251-266. [12] Han S,Xu W,Wang Z,et al.Crosstalk between the HIF-1and Toll-like receptor/nuclear factor-κB pathways in the oral squamous cell carcinoma mic...
(2011). An RNAi screen identifies USP2 as a factor required for TNF-alpha-induced NF-kappaB signaling. Int J Cancer 129, 607-618.Metzig M, et al. 2011. An RNAi screen identifies USP2 as a factor required for TNF-alpha-induced NF-kappaB signaling. Int. J. Cancer 129:607...
Geniposide inhibits high glucose-induced cell adhesion through the NF-kappaB signaling pathway in human umbilical vein endothelial cells. To investigate whether geniposide, an iridoid glucoside extracted from gardenia jasminoides ellis fruits, inhibits cell adhesion to human umbilical vein en... GF Wang,...
Blockade of TNF-alpha-induced NF-kappaB signaling pathway and anti-cancer therapeutic response of dihydrotanshinone I. International immunopharmacology. 2015; 28: 764-72.Wang, F.; Ma, J.; Wang, K.S.; Mi, C.; Lee, J.J.; Jin, X. Blockade of TNF-α-induced NF-κB signaling pathway ...
TNF-alpha regulates microglial activation via the NF-kappa B signaling pathway in systemic lupus erythematosus with depressionSystemic lupus erythematosusMicrogliaNeuroinflammationTumor necrosis factor-alphaPDTCThis study aimed to investigate the effects of tumor necrosis factor-alpha (TNF-alpha) on systemic ...
Lentiviral vectorBiopharmaceuticalsICH(Q2)The tumor necrosis factor alpha (TNF-α)/nuclear factor-kappa B (NF-κB) signaling pathway plays a crucial role in the pathogenesis of inflammatory diseases. Several therapeutic monoclonal antibodies (mAbs) and biosimilars against TNF-α have been developed to...
TNF receptor-associated factor-2 is involved in both IL-1 beta and TNF-alpha signaling cascades leading to NF-kappa B activation and IL-8 expression in human intestinal epithelial cells. J Immunol 1999; 162: 4447-4454Jobin C, Holt L, Bradham CA, Streetz K, Brenner DA, Sartor RB. TNF ...