Tissue-resident adult stem cell populations of rapidly self-renewing organs. Cell Stem Cell. 2010; 7 :656–670. [ PubMed ]Barker N., Bartfeld S., Clevers H. 2010a. Tissue-resident adult stem cell populations of rapidly self-renewing organs . Cell Stem Cell. 7 :656–670 10.1016/j....
Stem cells are primitive cells located in a specialized mesenchy... M Brittan,Wright, N. A - Gut 被引量: 281发表: 2004年 The Drosophila ovary: an active stem cell community. Only a small number of cells in adult tissues (the stem cells) possess the ability to self-renew at every ...
Tissue-resident mast cells are associated with many inflammatory and physiological processes. Although mast cells arise from the yolk sac, the exact ontogeny of adult mast cells remains unclear. Here we have investigated the hematopoietic origin of mast cells using fate-mapping systems. We have shown...
33Altmetric Metrics Abstract Tissue-resident macrophages are a heterogeneous population of immune cells that fulfill tissue-specific and niche-specific functions. These range from dedicated homeostatic functions, such as clearance of cellular debris and iron processing, to central roles in tissue immune su...
Stem cells of the liver, colon and small intestine gradually accumulate mutations throughout life at a similar rate even though cancer incidence varies greatly among these tissues. Accumulation of mutations in human adult stem cells in the course of a li
Aging alters tissue resident mesenchymal stem cell properties. Stem Cell Res. 2012;8(2):215–25. Article CAS Google Scholar Chen J, et al. Effects of donors’ age and passage number on the biological characteristics of menstrual blood-derived stem cells. Int J Clin Exp Pathol. 2015;8(11...
Besides hematopoietic stem cells (HSCs), mesenchymal stem cells (MSCs), endothelial progenitor cells (EPCs) and even solid-organ tissue resident stem cells (e.g. cardiac stem cells [CSC]) are known to contribute to solid-organ tissue repair. Stem cell delivery for cardiac tissue repair is by...
The multiple proposed sources of fibrogenic cells in adult life are schematically depicted in Figure1. Figure 1 Potential sources of MSCs in tissue repair. During injury or disease tissue-resident MSCs (mesenchymal stromal/stem cells) can expand and provide trophic support for regeneration and/or ...
These somatic stem cells exhibit shared fundamental behaviors, such as self-renewal, differentiation, quiescence, etc., which are regulated by both intrinsic cellular mechanisms and signals from specialized microenvironments. They serve as a group of resident cells with the ability to maintain tissue ...
Tissue resident mesenchymal stem cells (MSCs) are known to participate in tissue regeneration that follows cell turnover, apoptosis, or necrosis. It has been long known that aging impedes an organism's repair/regeneration capabilities. In order to study the age associated changes, the molecular cha...