关于至二次进展的时间 PFS2 ( Time to Second Disease Progression)的定义,以下描述最准确的是:A.从随机化分组开始,至因任何原因引起死亡的时间。B.从随机化分组开始,至出现影像学进展或因任何原因导致死亡的时间(以先发生的为准),对原发病灶、非区域淋巴结侵犯、
Using subject‐specific disease progression as an estimation of the disease time to model longitudinal neurodegeneration in ADdoi:10.1002/alz.080452Shafiee, NedaCollins, D LouisAlzheimer's & Dementia: The Journal of the Alzheimer's Association
aThe time to radiologic progression was defined as the time from randomization to disease progression (according to RECIST) on the basis of independent radiologic review. Data from patients who died without tumor progression were censored.The disease-control rate was defined as the 正在翻译,请等待....
2.Several research groups have recently reported that persistent GB virus C(GBV-C) co-infected with human immunodeficiency virus(HIV) leads to slower AIDSs disease progression than HIV-1 infection alone.本研究中的HIV-1感染者均未接受ART治疗,因而排除了治疗对疾病进展的影响。 3.Objective To evaluate...
Survival, and time to an advanced disease state or progression, of untreated patients with moderately severe multiple sclerosis in a multicenter observational database: relevance for design of a clinical trial for high dose immunosuppressive therapy with autologous hematopoietic stem cell transplantation ...
Objective response and time to progression on sequential treatment with sunitinib and sorafenib in metastatic renal cell carcinoma. Med Oncol. 2012;29:3321-4.Buchler T, Pavlik T, Bortlicek Z, Poprach A, Vyzula R, Abrahamova J, Melichar B (2012) Objective response and time to progression ...
However, the waiting time between CC diagnosis and access to treatment in authorized oncology care facilities may be a determining factor for disease progression [40], influencing the choice of non-surgical treatment and resulting in a poorer prognosis for cure. Despite these established guidelines, ...
Objective To characterize the period in which endovascular thrombectomy is associated with benefit, and the extent to which treatment delay is related to functional outcomes, mortality, and symptomatic intracranial hemorrhage. Design, Setting, and Patients Demographic, clinical, and brain imaging data as...
Using this approach, we were able to accurately stage embryos, quantitatively determine temperature-dependent developmental tempo, detect naturally occurring and induced changes in the developmental progression of individual embryos, and derive staging atlases for several species de novo in an unsupervised ...
It is clear that this protein is intricately linked to Parkinson’s disease progression and pathology. The endocannabinoid system is a relatively newly discovered system in neuropharmacology. The two major receptors, CB1 and CB2, are both G-protein-coupled receptors coupled to inhibitory G proteins,...