Anal high-grade squamous intraepithelial lesions (HSIL) are common in HIV-infected MSM and the presumed precursors to anal squamous cell cancer; however, direct progression of HSIL to anal cancer has not been previously demonstrated. The medical records were reviewed of 138 HIV-infected MSM ...
Data from this trial led to the European approval of pomalidomide in combination with low-dose dexamethasone in 2013 for patients with RRMM who have received at least two previous therapies, including bortezomib and lenalidomide, and who have demonstrated disease progression (Celgene Europe Ltd., ...
Our findings raise the question whether vascular hyalinosis plays a role in progression of diabetic nephropathy or could be a potential marker of disease progression. 1632 Transplant Glomerulopathy, Pathogenesis and Evolution N Nelles, S Dilioglou, M Afrouzian, L Gaber, R Barrios, L Truong. ...
Monotherapy with anti-inflammatory agents can elicit cell adaptability and/or affect tumour evolution in heterogeneous cancer types, leading to therapy resistance or even accelerated disease progression. Overcoming current obstacles to the clinical introduction of anti-inflammatory therapy will require the dev...
This indicates that op/op mice may be useful to examine the effects of microglia on neurodegenerative disease progression by breeding them to different transgenic mouse models. In addition, the lack of CSF-1 does not appear to affect CD200 expression by neurons but we did note a decrease in ...
An overview of the disease progression and factors affecting its pathogenesis, such as bacterial antigens, are mentioned. They also suggest that further research be made with regards to the matter.关键词: Humans Colitis, Ulcerative Cholangitis, Sclerosing Female Male ...
Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. Ann Neurol. 1996;39285- 294Google ScholarCrossref 82. Miller DH Magnetic resonance imaging and spectroscopy in multiple sclerosis. Curr Opin Neurol. 1995;8210- 215Google ScholarCrossref 83. Thomas DJPennock ...
miR-92a-3p promotes pulmonary fibrosis progression by regulating KLF2-mediated endothelial-to-mesenchymal transition Pulmonary fibrosis (PF) is a chronic lung disease that has a poor prognosis and a serious impact on the quality of life of patients. Here, we investigated ... S Pang,B Chen,Y ...
These results also demonstrated that RBCs isolated from healthy individuals could be manipulated to alter their cytokine profile and their influence on T-cells. Similar dysregulation of RBC activity has been demonstrated in disease (carotid atherosclerosis)6, following surgery7, or following haemodialysis...
Having demonstrated the association of smoking status with age at diagnosis, gender, LNMets and TNM stage, we sought to investigate whether the association is ADC specific. For this purpose, we examined the effect of smoking status on SQC. The 50 patients with SQC consisted of 34 smokers and...