Onset and progression of disease in familial and sporadic Parkinson's disease. Am J Med Genet A 2004;124:255-258.Inzelberg R, Schecthman E, Paleacu D, Zach L, Bonwitt R, Carasso RL, et al. Onset and progression of disease in familial and sporadic Parkinson's disease. Am J Med ...
et al. Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS. Nat Med 11, 423–428 (2005). https://doi.org/10.1038/nm1207 Download citation Received27 August 2004 Accepted17 February 2005 Published13 March 2005 Issue Date...
CXCL12 exerted protective anti-inflammatory effects in Alzheimer’s disease (e.g. promoting microglial phagocytosis of amyloid beta plaques) but attracted pro-inflammatory microglia involved in the disease onset and progression of amyotrophic lateral sclerosis (ALS) [10]. Recently, it was shown that ...
If an intervention could delay both disease onset and progression by a modest 1 year, there would be nearly 9.2 million fewer cases by 2050 [15]. In cases of AD, several risk factors (e.g., hypertension, obesity, diabetes, smoking, physical inactivity, and depression) are modifiable [16,...
Onset of Coronary Heart Disease is Associated with HCMV Infection and Increased CD14+CD16+ Monocytes in a Population of Weifang, China[J]. Biomedical and Environmental Sciences, 2020, 33(8): 573-582. doi: 10.3967/bes2020.076 Citation: LI Hong Zheng, WANG Qin, ZHANG Yi Yuan, WANG Jin ...
The effect of stress on the onset and progression of Creutzfeldt-Jakob disease: results of a German pilot case-control study. (1999) The effect of stress on the onset and progression of Creutzfeldt-Jakob disease: results of a German pilot case-control study . Eur J Epidemiol ... C Laske,...
The main search terms included “Adult Onset Still Disease,”“AOSD,”“Still's disease,”“Wissler Fanconi syndrome,”“epidemiology,”“diagnosis,”“clinical and laboratory manifestations,”“disease continuum,”“disease burden,”“diagnostic biomarkers,” and “treatment” (see Supplementary Material...
The conference brought together experts on osteoarthritis from diverse backgrounds and provided a multidisciplinary and comprehensive summary of recent advances in the prevention of osteoarthritis onset, progression, and disability. Part 1 focuses on a new understanding of what osteoarthritis is and on ...
The test has, however, been validated in several other mouse models as a measure of sensorimotor function- and spontaneous activity32. SOD1 G93A mice develop tremor in their hind legs as one of their characteristics30. Interestingly, the SOD1 + P mice (median onset = 89 days) ...
Exercise has emerged as a promising lifestyle candidate to modify disease onset and progression2. Research using HD mouse-models demonstrates that cardiovascular exercise alters biomarkers of neuroplasticity, such as brain derived neurotrophic factor (BDNF)3,4, and delays signs of disease5,6,7,8. ...