The tight junction (TJ) constitutes the barrier both to the passage of ions and molecules through the paracellular pathway and to the movement of proteins and lipids between the apical and the basolateral domains of the plasma membrane. In recent years more than 40 different proteins have been ...
Tight junction (TJ) proteins (Tjps), Tjp1 and Tjp2, are tight junction-associated scaffold proteins that bind to the transmembrane proteins of tight junctions and the underlying cytoskeleton. In this study, we first analyzed the tumorigenic characteristics of B16-F10 melanoma cells, ...
Tight junctions and tight junction proteins in mammalian epidermis. 机译:哺乳动物表皮中的紧密连接和紧密连接蛋白。 获取原文 获取原文并翻译 | 示例页面导航 摘要 著录项 相似文献 相关主题 摘要 Tight junctions (TJ) are barrier forming cell-cell junctions that are found in a variety of cell types...
Subcellular location Cell membrane, Cell junction Applications IHC/IF Human, Mouse, Rat 1: 500-1: 1200 colon, duodenum, small intestine Background Tjp1, TjpP2, and Tjp3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhes...
Most tight junction (TJ) proteins build epithelial and endothelial barriers. Some, however, form paracellular ion or water channels. Besides barrier and channel properties, numerous other functions gain increasing interest: TJ proteins can serve as receptors for pathogens and mediate immunological reaction...
Association of tight junction (TJ) proteins with a distinct membrane compartmentcirrhosisspontaneous bacterial arthritisSeptic arthritis is usually of hematogenous origin and is increasingly being reported in elderly patients, who often have underlying medical conditions such as diabetes or alcoholism. We ...
Organ culturing of the amnion at 37 weeks gestation induced the relocalization of the TJ proteins from the cytoplasm to the lateral membranes. Furthermore, in cultured amniotic epithelial cells, dexamethasone induced the downregulation of the protein expression of TJs. These findings suggest that t...
Characterization of tight junction proteins in cultured human urothelial cells . In Vitro Cell Dev Biol Anim 44 : 261–267, 2008.Rickard A, Dorokhov N, Ryerse J, Klumpp DJ, McHowat J. Charac- terization of tight junction proteins in cultured human urothelial cells. In Vitro Cell Dev Biol...
Airway epithelial tight junction (TJ) proteins form a resistive barrier to the external environment, however during respiratory bacterial infection TJ abundance is altered. Metformin used for the treatment of diabetes is known to increase transepithelial resistance (TEER) of airway epithelial cells. We ...
The tight junction (TJ) constitutes the barrier both to the passage of ions and molecules through the paracellular pathway and to the movement of proteins and lipids between the apical and the basolateral domains of the plasma membrane. In recent years more than 40 different proteins have been ...