Effects of thyroid hormones on the multiple molecular forms of mitochondrial malate-dehydrogenase.VarroneConsiglioCovelliHormones
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- 《Molecular Psychiatry》 被引量: 238发表: 2006年 PCB-related alteration of thyroid hormones and thyroid hormone receptor gene expression in free-ranging harbor seals (Phoca vitulina). Persistent organic pollutants are environmental contaminants that, because of their lipophilic properties and long ...
Thyroid hormone metabolism comprises all biochemical reactions of thyroid hormones and iodothyronines, which are catalyzed by various classes of enzymes of the vertebrate organism and its microflora. These enzymes alter the biochemical properties of the thyroid hormones thyroxine (T4) and 3,3′,5-...
hormone secretion. Furthermore, THBPs form an important extrathyroidal pool of thyroid hormone and may facilitate its uniformcellular distribution. THBPs may also help to avoid iodine wastage by conferringmacromoleculeproperties to the small thyroid hormone molecules, thus reducing renal iodine loss. ...
Type 2 deiodinase (D2), encoded by DIO2 gene, catalyzes the activation of the prohormone thyroxine (T4) into the bioactive hormone triiodothyronine (T3) in peripheral tissues, thereby regulating the intracellular Thyroid Hormone (TH) availability. Recently, several studies have demonstrated that a ...
Use of thyroid hormone 3,5,3'-trioodo-L-thyronine (T3); Methodology of the study; Import of precursor proteins in the matrices and outer membranes of cardiac mitochondria; Protein levels of components of the protein import machinery.被引量: 125 ...
The Molecular Genetics of Hypoparathyroidism Application of developments in molecular biology to the study of hypoparathyroid disorders enables characterization of some of the mechanisms involved in the regulation of parathyroid gland development, of parathyroid hormone (PTH) secre... RV Thakker 被引量:...
Thyroid hormone replacement stimulates catch-up growth and bone maturation, but recovery may be incomplete dependent on the duration and severity of hypothyroidism prior to treatment. A severe phenotype characteristic of hypothyroidism occurs in children with resistance to thyroid hormone due to mutations ...
Thyroid hormone receptors (TRs) are members of the nuclear receptor superfamily that mediate the pleiotropic activities of the thyroid hormone, T3, in differentiation, growth, and metabolism (Yen, 2001). From: Molecular and Cellular Endocrinology, 2009 ...