Structural analyses were carried out on the R218H and R218P mutations in complex with T4(48). 8. Cheng S, Pages RA, Saroff HA, et al. Analysis of thyroid hormone binding to humanserum prealbumin by 8- anilinonaphthalene-1-sulfonate fluorescence.V CodyHotthyroidology Com...
Thyroglobulin (TG) is the protein precursor of thyroid hormones, which are essential for growth, development and the control of metabolism in vertebrates1,2. Hormone synthesis from TG occurs in the thyroid gland via the iodination and coupling of pairs of tyrosines, and is completed by TG proteo...
Phosphorylation stimulates the transcriptional activity of the human beta 1 thyroid hormone nuclear receptor. Lin,K.,H.,... - 《Proceedings of the National Academy of Sciences》 被引量: 149发表: 1992年 Structure of the hormone binding domain of human beta 1 thyroid hormone nuclear receptor: is...
Structure of the thyroid gland, serum thyroid hormone and the reproductive cycle of Atlantic sting ray, Dasyatis sabina J. Exp. Zool. Oct. 1999; 1; 284 (5): 505-16.Volkoff H, Wourms JP, Amesbury E, Snelson FF 1999 Struc- ture of the thyroid gland, serum thyroid hormones and th...
Structure of human transthyretin complexed with bromophenols: a new mode of binding The binding of two organohalogen substances, pentabromophenol (PBP) and 2,4,6-tribromophenol (TBP), to human transthyretin (TTR), a thyroid hormone transpo... M Ghosh,IATM Meerts,A Cook,... - 《Acta Crystal...
FIG. 1. Structure of the common ␣- and thyroid-stimulating hormone (TSH) -subunit genes. Exons are denoted by the boxes, and introns or flanking DNA sequences are denoted by lines. The length of exons and introns are shown in base pairs. Coding regions of exons are shaded; noncod...
organs containing differentiated hormone-secreting cells, such as the anterior pituitary gland and pancreatic islets of Langerhans, but also in numerous other tissues spread throughout the human body, for example, fat, muscle, and intestine. This significantly widens the definition of an endocrine ...
The biological importance of L-thyroxin, the principal hormone secreted by the thyroid gland, is well established, but the mechanisms of thyroid-hormone action are still largely unexplained. We have crystallized L-thyroxin and determined its three-dimensional structure by x-ray crystallography in the...
Modular structure of a chicken lysozyme silencer: involvement of an unusual thyroid hormone receptor binding site. Silencer elements, by analogy to enhancer elements, function independently of their position and orientation. We show that the chicken lysozyme silencer S-... A Baniahmad,C Steiner,AC ...
Progress in understanding structure-function relationships of human thyroid-stimulating hormone This paper summarizes current advances in the structure-function relationships of human thyroid-stimulating hormone (TSH) in the context of studies on structurally related gonadotropins. Investigators have now identif...