10 In 1973, Van Herle and colleagues11 described the earliest specific and reproducible double antibody radioimmunoassay for measurement of thyroglobulin in human serum; it had an analytical sensitivity of 1.6 ng/mL. The same group later showed that patients with untreated differentiated thyroid cancer...
SUMMARYIgG antibody to human thyroglobulin was labelled with 131Iodine (131I) and used to locate deposits of thyroid follicular and papillary tumours with ... DS Fairweather,AR Bradwell,SF Watson-James,... - 《Clinical Endocrinology》 被引量: 19发表: 1983年 Should 'low-risk' thyroid cancer ...
Conclusions:Our preliminary results indicate that an undetectabIe Tg concentration measured using the second-generation assay is unlikely to be a false-negative result induced by TgAb-interferences. Keywords:differentiated thyroid cancer;thyroglobulin;thyroglobulin antibodies...
Sweeping antibody as a novel therapeutic antibody modality capable of eliminating soluble antigens from circulation. Immunol Rev. 2016;270(1):132–51. Article CAS PubMed Google Scholar Spencer C, Petrovic I, Fatemi S, LoPresti J. Serum thyroglobulin (Tg) monitoring of patients with ...
CONCLUSION: The present data do not confirm strong associations between thyroid antibody elevations and preterm birth found in three of five previously published reports. Preterm premature rupture of membranes appears to contribute to the thyroid antibody-associated early deliveries, possibly as a result ...
When a high titer antibody is present, an appended comment reflecting the potential for positive or higher than reported Tg can help to ensure that the clinician is not falsely reassured by a low Tg level. 2.4.6.5 Reduction of thyroid hormone replacement doses in patients with thyroid cancer ...
After changing their detection antibody, the presence of a high Tg was demonstrated, in agreement with non-isotopic techniques. The expertise conclusion was a lack of detection by the IRMA Tg assay. This incident was notified to AFSSAPS by the manufacturer. 展开 ...
The test is typically performed using immunoassay, which is subject to interference by thyroglobulin antibody (TgAb) and heterophile antibody (HAb). TgAb is routinely checked to validate the test result. Pre-treatment of specimen with HAb blocking agents is adop...
thyroglobulin TgAb: anti-thyroglobulin antibody Tg-FNA: thyroglobulin measurement with fine-needle aspiration References Chen W, Zheng R, Baade PD, Zhang S, Zeng H, Bray F, Jemal A, Yu XQ, He J. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66(2):115–32. Article Pub...
Additionally, a relevant problem in monitoring DTC patients is represented by the presence of thyroglobulin antibody (TgAb). TgAb is present in up to 15–25% of patients with DTC and may interfere on Tg immunoassays resulting in falsely low or undetectable Tg results [4]. In such cases, TgAb...