19–21 In patients with thyroglobulin antibodies, serial monitoring of antibody levels in a single assay, can also sometimes be informative about the presence of residual disease and its progression or response to therapy.22–24 The ATA’s 2015 clinical practice guideline uses the postoperative ...
Thyroglobulin antibody status and differentiated thyroid cancer: what does it mean for prognosis and surveillance? Curr Opin Oncol. 2015;27(1):26–32. Article CAS PubMed Google Scholar Lupoli GA, Okosieme OE, Evans C, Clark PM, Pickett AJ, Premawardhana LD, et al. Prognostic significance ...
What to Expect With the Antithyroglobulin Antibody Test When you arrive for your antithyroglobulin antibody test, a nurse or lab technician will have you sit comfortably in a chair. They will gather a few supplies to take a blood sample from your vein. First, they will put ...
Log-rank was used to determine an association between persistent antibody elevation and recurrence. Results Of 247 patients (77% women, 23% men; mean 45.7 ± 1.0 y) with TgAb measured preoperatively, 34 (14%) were TgAb+ (≥20 IU/mL; mean 298.1 ± 99.2 IU/mL). Median...
The antibody response to group C meningococcal polysaccharide vaccine was studied in a Nigerian village. Household clustering of poor responders to immuniz... Greenwood B.M.,Bradley A.K.,Blakebrough I.S.,... - 《Transactions of the Royal Society of Tropical Medicine & Hygiene》 被引量: 248...
When a high titer antibody is present, an appended comment reflecting the potential for positive or higher than reported Tg can help to ensure that the clinician is not falsely reassured by a low Tg level. 2.4.6.5 Reduction of thyroid hormone replacement doses in patients with thyroid cancer ...
Antigen-Antibody ReactionsEthnic GroupsEuropean Continental Ancestry GroupAdolescentAdultChildBackground Using recombinant human monoclonal thyroglobulin antibodies expressed as Fab molecules (TgAb-Fab), we have recently confirmed the restriction of Tg epitopes in Hashimoto's thyroiditis (HT). Objective To ...
Results:The decrease in Tg concentrations in the presence of TgAb was more pronounced in the first-generation Tg assay (41.6%) compared with the second-generation assay (31.4%) (p<0.01). Accordingly, the mean Tg-recovery values were 51.4% in the first-generation Tg assay and 68.8% in the...
Additionally, a relevant problem in monitoring DTC patients is represented by the presence of thyroglobulin antibody (TgAb). TgAb is present in up to 15–25% of patients with DTC and may interfere on Tg immunoassays resulting in falsely low or undetectable Tg results [4]. In such cases, ...
positive Tg antibody (Tg-Ab > 115 IU/ml) and distant metastasis. Patients were classified into different stages (I, II, III, IVA and IVB) according to American Joint Committee on Cancer (AJCC) TNM staging. All patients were treated with total or near-total thyroidectomy, RAI remnant ablatio...