Astrocytes were classified into a single morphological population in which each cell subserved multiple functions. The results of this study do not support the contention that astrocytes can be subdivided into two morphological and functional subtypes, namely type-1 and type-2, which have processes ...
As astrocytes are known to modulate BBB functions, we further set a culture system that included RBE4.B BCECs, neurons and astrocytes. In order to test formation of BBB, we measured the amount of 3H-sucrose able to cross the BCEC layer in this three-cell type model of BBB. Herein we ...
Astrocytes represent a major nonneuronal cell population in the central nervous system (CNS) and are actively involved in several brain functions. These ce... J Mantz,J Cordier,C Giaume - 《Anesthesiology》 被引量: 237发表: 1993年 Disruption of gap junctional intercellular communication by lindan...
A three-dimensional single-cell-resolution mammalian brain atlas will accelerate systems-level identification and analysis of cellular circuits underlying various brain functions. However, its construction requires efficient subcellular-resolution imaging throughout the entire brain. To address this challenge, ...
are capable of infection with authentic SARS-CoV-2. Before infection, PLCs elicited astrocytic maturation and production of basement membrane components, features attributed to pericyte functions in vivo. While traditional cortical organoids showed little evidence of infection, PLCs within cortical organoi...
There has been no effective drug to ameliorate sensorimotor functions except for rehabilitation, leaving most of the patients suffering from life-long disability. In this sense, cell therapy has emerged as a promising therapy for stroke in the subacute phase. Mesenchymal stem cells (MSCs) have ...
It was reasoned that anoikis was contributing to cell death and that precise control of intercellular contacts in cultures the might improve hepatic functions of engineered liver tissues. Accordingly, a system was developed that enables the formation of intercellular contacts prior to patterning as well...
Prenatal and postnatal exposures to a mixture of PCBs, organochlorine pesticides, including HCB and DDE, and methylmercury changed gene expression of the rat cerebellum in Purkinje cells, oligodendrocytes, and astrocytes, and these effects varied by sex [46]. However, because all of these ...
A Guide to the Composition and Functions of the Extracellular Matrix. FEBS J. 2021, 288, 6850–6912. [Google Scholar] [CrossRef] Milošević, N.J.; Judaš, M.; Aronica, E.; Kostovic, I. Neural ECM in Laminar Organization and Connectivity Development in Healthy and Diseased Human ...
It is produced by endothelial cells, neurons and astrocytes in the central nervous system, hepatocytes and Sertoli cells. It has an important role in the paracrine regulation of cardiovascular functions in humans. Specifications Product ID E5219 Product Name Endothelin-1, human Formula Wt. 249...