生物学靶点(英語:Biological target)是指位于生物体内,能够被其他物质(配体、药物等)识别或结合的结构。常见的药物靶点包括蛋白质、核酸和离子通道等。---维基百科 其次关于TTD数据库,官方简介为 TTD是一个提供目前已知或者处于探索阶段的、具有治疗价值的蛋白或核酸靶点的相关信息;包括靶点相关疾病、介导的生物学通路信...
To complement other databases, we constructed the Therapeutic Target Database (TTD) with expanded information about (i) target-regulating microRNAs and transcription factors, (ii) target-interacting proteins, and (iii) patented agents and their targets (structures and experimental activity values if ...
GBM targets were sourced from three online databases: the Therapeutic Target Database (TTD, https://db.idrblab.net/ttd/), DisGeNet database (https://www.disgenet.org/), and GeneCards database (http://www.genecards.org/). The UniProt database (https://www.uniprot.org/) was used to ...
We first searched interactions of curcumin in three different databases, including the STITCH database (http://stitch.embl.de/ accessed on 20 May 2022), therapeutic target database (TTD) (http://db.idrblab.net/ttd/ accessed on 20 May 2022), and drug-gene interaction database (DGIdb) (ht...
Rheumatoid arthritis (RA) is a chronic autoimmune disease with a global prevalence of approximately 0.46%, causing significant impairments in patients’ quality of life and an economic burden. Saussurea involucrata (SI) has long been used in traditional