Methods and Results: PLT function was evaluated by whole-blood flow cytometry to detect PLT CD62 expression and by impedance aggregometry to assess platelet aggregation (PA) before and after bolus intravenous administration of low-dose heparin (2713 ± 1231 U) in 16 patients undergoing coronary ...
This exploratory study of a multiplatform randomized trial investigating the effects of therapeutic-dose heparin in early-pandemic hospitalized COVID-19
This randomized clinical trial evaluates the effects of therapeutic-dose low-molecular-weight heparin vs standard prophylactic or intermediate-dose
After completion of apomorphine-induced rotational behavior, the mice from the sham (Vehicle + corn oil), 6−OHDA, and 6−OHDA + honokiol treated groups were anesthetized and transcardially perfused with heparin solution, and subsequently followed by ice cold fixative (4% paraformaldehyd...
Osteonecrosis of the femoral head (ONFH) is a multifactorial disease leading to severely limited function. By far, the etiology and pathogenesis of ONFH are not fully understood, and surgery is the only effective way to treat ONFH. This study aims to ide
e. The Stroke Council stressed that data about the safety and efficacy of heparin in ischemic strokes was insufficient and conflicting, potentially dangerous, noting the frequency of parenchymal hemorrhage. f. The panel also refused to recommend the use of nimodipine, barbiturates, naloxone, glutama...
(EDTA)-coated tubes for hematology and heparin-coated tubes for clinical chemistry. Blood samples were collected in anticoagulant tubes to determine the parameters of erythrocyte count (RBC), hematocrit (HCT), hemoglobin, mean cell volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular ...
Possible Dissociation of the Heparin-binding and Mitogenic Activities of Heparin-binding (Acidic Fibroblast) Growth Factor-1 from Its Receptor-binding Activities by Site-directed Mutagenesis of a Single Lysine Residue. J. Cell Biol. 111:2129-2138, 1990 (Year: 1990). Lazar et al. Transforming ...
Fig. 1. A summary of membrane interactions. A) The bacteriophage T4 binding to lipopolysaccharide. B) Adenovirus binding to coxsackievirus and AdV receptor. C) Cholera toxin binding to a ganglioside GM1 receptor. D) Diphtheria toxin binding to human membrane-anchored heparin-binding EGF-like growth...
Other GAGS may include Dermatan sulphate, Heparin sulphate, Heparin or their Proteoglycan forms, Keratan sulphate. Keratan sulphate and the like, while not technically a glycosaminoglycuronoglycan, will be considered to be included as a GAG herein. Other scavenger receptor ligands may also be ...