we mainly discuss the current knowledge of therapeutic applications of exosomes from different cell types,different exosomal administration routes,and current advances of exosome tracking and targeting in ischaemic stroke.We also briefly summarised the pathology of ischaemic stroke,exosome biogenesis,exosome ...
Applications of exosomes in the delivery of mRNA Therapeutic use of mRNA inspired a substantial hope against striving various incurable diseases. mRNA as a therapeutic agent, recent breakthroughs in nanotechnology and molecular sciences have made it possible to produce practically any functional protein or...
Exosomes which are membrane vesicles released by cells have gained significant interest in the field of cancer therapy as a novel means of intercellular communication. Their role in immune activation and their pathophysiological functions in cancer thera
Finally, non-cancer clinical applications of exosomes are highlighted. Exosomes are a classtype of extracellular vesicles (EV) that are very small (30–150 nm) and secreted from most cells into bodily fluids, such as blood, saliva, and urine (De Toro et al., 2015; Liu et al., 2018b;...
(EVs), that include exosomes provide hope in both diagnostic and therapeutic aspects. They are natural lipid nanovesicles secreted by all cell types and carry molecules that reflect the status of the parent cell. This facilitates their potential use as biomarkers for an early diagnosis. Additionally...
Various critical applications of exosome and exosome-like particles have been extensively investigated. Exosomes have shown therapeutic potential in treating several diseases, including cancer, respiratory disease, degenerative diseases, and cardiovascular disease. Exosomes derived from stem cells can promote ti...
We also highlight recent studies that have demonstrated the utility of exosomal biomarkers in different types of cancer, such as lung cancer, breast cancer, and pancreatic cancer. Overall, exosomes show great promise as noninvasive biomarkers for cancer detection and monitoring. Exosomes have the ...
Some embodiments of the methods and compositions provided herein relate to treating a subject suffering from hypertension, a cardiac injury, or a metabolic disorder through, for example, administering one or more exosomes or one or more oligonucleotides to a subject in need of treatment. BACKGROUND...
Exosomes participate in many physiological and pathological processes by regulating cell–cell communication, which are involved in numerous diseases, including osteoarthritis (OA). Exosomes are detectable in the human articular cavity and were observed
Topical and transdermal applications of exosomes furnish a promising route for targeted delivery of their regenerative effects directly into the skin. Drugs can penetrate the skin through several modes. The primary modes of skin penetration include paracellular, transcellular, trans-appendageal and the ...