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However, this review wants to critically emphasize two important points actually hampering further discussion in the field : (i) the clinical data are virtually absent at the moment ; (ii) the best cellular source of exosomes to be used to deliver drugs is really far to be defined. Facing ...
The short answer is that stem cells are undifferentiated cells with power to make other kinds of cells. Most cells cannot do that as they can only make more of themselves. What this means is that stem cells can be used to make specialized cells. These include neurons, heart cells, and mo...
Carbohydrates are often less immunogenic than proteins, and less likely to stimulate high-affinity antibodies. Moreover, the structure of carbohydrates tends to be similar to that of the host, which may lead to autoimmunity45. Exosome vaccines Exosomes can migrate through the intestinal basement ...
Tumor cells are known to release more exosomes than healthy cells. The exosomes can indicate not only cancers, but also other disease processes like inflammation and neurodegeneration.The methods used for the detection are Next-Generation Sequencing (NGS), digital Polymerase Chain Reaction (dPCR), ...
some trials they have shown really promising results, especially for wound healing, for example. But studies have shown that the key therapeutic effects in these therapies are not really caused by the stem cells themselves, but by the secretions from these MSCs, which a...
In fact, it has already been reported that spike proteins can be found in exosomes of vaccinated individuals… This has massive implications for shedding and begs the questions: Is this why there are so many people who feel the effects of someone else’s modRNA injection after spending a ...
Brain electrodes have been around for a while and are often used to treat disorders such as Parkinson’s disease and some severe cases of epilepsy.Those devices tend to involve sticking electrodes deep inside the brain to access regions involved in those disorders. ...
one type of search onClinicaltrials.gov. Because MSCs go by different names this likely an underestimation. On the other hand, some of these trials may be non-interventional. Other MSC trials don’t use actual cells but instead are based on products derived from those cells like exosomes. ...
Made up of lipid bilayer-delimited particles, extracellular vesicles are nanometre sized messengers naturally released from cells. To unravel the regenerative properties of EVs the team used a specially designed heart-on-a-chip model embedded with sensors to track tissue contractions. They found that ...