The thermodynamics of DNA structural motifs. Annu. Rev. Biophys. Biomol. Struct. 33, 415–440 (2004). Article CAS PubMed Google Scholar Friedberg, E. C. & Fischhaber, P. L. DNA replication fidelity. eLS 69, 497–529 (2005). Google Scholar Arias-Gonzalez, J. R. Information ...
The thermodynamics of DNA structural motifs. Annu. Rev. Biophys. Biomol. Struct. 33, 415–440 (2004). CAS Google Scholar Dirks, R. M. & Pierce, N. A. A partition function algorithm for nucleic acid secondary structure including pseudoknots. J. Comput. Chem. 24, 1664–1677 (2003). ...
Structural modifications of proteins and peptides provide an alternative to excipient use, where it is needed and feasible, such as in the production of DPIs, supercritical fluid drying and other particle engineering applications. These modifications may also be employed when the amount/type of ...
THERMODYNAMICSBINDING energyDivalent magnesium ions (Mg2 ) serve a vital role in defining the structural and catalytic chemistry of a wide array of RNA molecules. The body of structural information on RNA motifs continues to expand and, in turn, the functional importance of Mg2 is revealed. A ...
Thus, peptide-induced membrane activity is boosted by properties intrinsic to the peptide (e.g., charge and structural changes associated with metallation) and bilayer (e.g., reversal of sn-2 chain due to oxidation). Third, we show using oriented-sample 15N solid-state NMR that the helical...
The programmability of Watson–Crick base pairing, combined with a decrease in the cost of synthesis, has made DNA a widely used material for the assembly of molecular structures and dynamic molecular devices. Working in cell-free settings, researchers in DNA nanotechnology have been able to scale...
of 53 StSET genes containedcis-elements described previously in the context of light-responsiveness. In addition, we found several drought-responsive, abscisic acid-, salicylic acid-, methyl jasmone acid- and auxin-responsive elements (Fig.4). In addition, we identified 20 conserved motifs with ...
III and the C domain comprises CR I, IV, and V [16]. While components of the tertiary fold are overwhelmingly helical it is interesting that both domains have many nonhelical parts: CR II and III form two interleaving T-loop motifs whereas CR I, IV, and V are part of loops and ...
profile of DNA around experimentally mapped TSSs reflect local structural traits, which can be considered typical features of CPs. These findings have been corroborated by several other works [7–9], illustrating that profiles of physicochemical properties indeed reveal a TSS specific signal in several...
The thermodynamics of DNA structural motifs. Annu. Rev. Biophys. Biomol. Struct. 2004, 33, 415-440. 81. SantaLucia, J.; Allawi, H.T.; Seneviratne, A. Improved nearest-neighbor parameters for predicting DNA duplex stability. Biochem. 1996, 35, 3555-3562. 82. Giesen, U.; Kleider, W....