The role of RNA and protein synthesis in differentiating spores of the fungusPhytophthora palmivora was investigated using inhibitors, precursor assimilation, andin vitro translation of directly extracted RNA.
These findings offer an informative snapshot of the protein-RNA interactome, which can provide a basis to better understand the roles of RNA-binding proteins in the nervous system.Quan, Jie
To understand the role of tRNA in protein synthesis, we can break down the process into several key steps:1. Transcription of DNA to mRNA: The process of protein synthesis begins with the transcription of DNA into messenger RNA
Regulatory RNA is emerging as the major architect of cognitive evolution and innovation in the mammalian brain. While the protein machinery has remained largely constant throughout animal evolution, the non protein-coding transcriptome has expanded considerably to provide essential and widespread cellular ...
for novel RNA-based therapies, enabling tailored interventions for specific cancer subtypes. This review provides a comprehensive overview of the roles and mechanisms of various coding and noncoding RNA modifications in cancer progression and highlights recent advancements in RNA-based therapeutic ...
Noncoding RNAs are transcribed in the most regions of the human genome, divided into small noncoding RNAs (less than 200 nt) and long noncoding RNAs (more than 200 nt) according to their size. Compelling evidences suggest that small noncoding RNAs play critical roles in tumorigenesis and...
Radi et al. 2025 The study demonstrates that the U-CUP perfusion bioreactor enhances osteogenic differentiation and alters the osteoblast proteome compared to static culture, supporting its use as a more physiologically relevant 3D bone model. (Title: The proteome of osteoblasts in a 3D culture perf...
One of the key features of cancer is energy metabolic reprogramming which is tightly related to cancer proliferation, invasion, metastasis, and chemotherapy resistance. NcRNAs are a class of RNAs having no protein-coding potential and mainly include micr
Type 2 diabetes mellitus (T2DM), one of the main types of Noncommunicable diseases (NCDs), is a systemic inflammatory disease characterized by dysfunctional pancreatic β-cells and/or peripheral insulin resistance, resulting in impaired glucose and lipid
Wu and Kuo Journal of Biomedical Science (2020) 27:49 https://doi.org/10.1186/s12929-020-00636-z REVIEW Functional roles and networks of non- coding RNAs in the pathogenesis of neurodegenerative diseases Yi-Ying Wu1 and Hung-Chih Kuo1,2* Open Access Abstract Recent transcriptome analyses ...