To understand the role of tRNA in protein synthesis, we can break down the process into several key steps:1. Transcription of DNA to mRNA: The process of protein synthesis begins with the transcription of DNA into messenger RNA
the role of protein synthesis in early estrogen actiondoi:10.1073/pnas.47.2.164G.C. MUELLERWisconsinMechanisms of Hormone ActionG.C. MUELLER . 1965. The Role of RNA and Protein Synthesis in Estrogen Action. Mechanisms of Hormone Action, 228-245. /...
Gene expression is one of the most critical cellular processes. It is controlled by complex mechanisms at the genomic, epigenomic, transcriptomic, and proteomic levels. Any aberration in these mechanisms can lead to dysregulated gene expression. One rece
Specific RNA-binding and ribosomal proteins seem to play a key role in controlling gene expression to determine the differentiation fate of the cell. This demonstrates the important role of RNA-binding proteins, specific ribosome-binding proteins and microRNAs as key molecules in controlling the ...
NeurodegenerationIn this review, the role of aberrant RNA metabolism in ALS is examined, including the evidence that a majority of the genetic mutations ... MJ Strong - 《Journal of the Neurological Sciences》 被引量: 271发表: 2010年 The role of RNA and RNA processing in neurodegeneration. J...
MOS2 (At1g33520) was first identified in a genetic screen for mutants that are defective in innate immu- nity [31]. It encodes a nuclear protein with G-patch and KOW domains that are indicative of RNA binding [31]. In this study, we show that MOS2 is involved in pri- miRNA ...
Role of RNA-binding proteins in neurological disorders, COVID-19, and cancer. Hum Cell. 2023;36(2):493–514. Article CAS PubMed Google Scholar Llamusi B, Bargiela A, Fernandez-Costa JM, Garcia-Lopez A, Klima R, Feiguin F, et al. Muscleblind, BSF and TBPH are mislocalized in ...
This study aimed to evaluate the role of TREM2 in the tumor microenvironment in the context of HCC progression. Methods HCC was experimentally induced in wild-type (WT) and Trem2-deficient (Trem2−/−) mice, and clinical sample analysis and in vitro studies on macrophages were conducted....
microRNAs (miRNAs) play important roles in the regulation of gene expression. In Arabidopsis, mature miRNAs are processed from primary miRNA transcripts (pri-miRNAs) by nuclear HYL1/SE/DCL1 complexes that form Dicing bodies (D-bodies). Here we report that an RNA-binding protein MOS2 binds to...
Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome Thu Giang Nguyen, Christina Ritter & Eva Kummer Nature Communications volume 14, Article number: 7991 (2023) Cite this article 4521 Accesses 3 Citations 51 Altmetric Metrics details Abstract...