This chapter discusses the role of enzymes in carbohydrate metabolism and related biological processes. The chapter discusses how a number of enzymes can act together to carry out an integrated and complicated process. In an intact biological system there are several ways in which the reduced ...
Hepatic microsomal enzymes play an important role in thyroid hormone homeostasis. Glucuronidation of thyroxine is the rate limiting step in the biliary exc... R.,Michael,McClain - 《Toxicologic Pathology》 被引量: 216发表: 1989年 Studies on the metabolism of haloperidol (HP): the role of CYP3A...
such as Parkinson’s disease (PD), are associated with alterations in cellular metabolism. These changes have been recognized as a novel hot topic that may provide new insights to help identify risk in the pre-symptomatic phase of the disease, understand...
The role of Ca 2+ in control of malic enzyme activity in bovine adrenal cortex mitochondria Low physiological levels of Ca 2+, in the presence of Mg 2+ allow the reduction of extramitochondrial NADP+ via intramitochondrial malic enzyme. The rate o... D Pfeiffer - 《Biochem Biophys Res ...
of enzymes known as dihydroceramide synthases. In addition, alterations in ceramide synthesis, trafficking and metabolism in specific cellular compartments exert distinct consequences on metabolic homeostasis. Here, we examine the emerging concept of how the intracellular localization of ceramides with ...
The role of BCAAs and their metabolism in metabolic health and lifespan has been extensively studied recently. These studies were mainly conducted in model organisms, including rodents, due in part to the convenience of obtaining mechanistic insights by using genetically modified animal models. Further...
However, more in-depth studies showed this viewpoint to be too one-sided. Emerging evidence suggests that lysosomes may also be the cellular center for intracellular transport (Fig. 1), signaling (Fig. 2), and metabolism. Fig. 1 Lysosomes play a crucial role in intracellular transport. ...
What insights can we gain about enzymes and their role in animal nutrition? Dr. Amy Petry, assistant professor in the department of animal and food sciences at Texas Tech University, discusses how these enzymes can enhance gut health and fiber fermentability in pigs and improve the energy contri...
Genetics of alcoholism. Two genes that encode enzymes of alcohol metabolism have the strongest effect on AUD: aldehyde dehydrogenase 2 and alcohol dehydrogenase 1B each has ... HJ Edenberg - 《Science》 被引量: 190发表: 1998年 Role of Alcohol Metabolism in Non-Alcoholic Steatohepatitis Non-alc...
The renin-angiotensin system (RAS) was identified for the first time by Tigerstedt and Bergman (1898) [1] in the rabbit’s kidney. Phylogenetically, the RAS is a very old hormone system, present in primitive vertebrates such as the lamprey, playing a key role in the adaptation from aquatic...