The origins of microgliaNo abstract is available for this article.doi:10.1111/j.1468-2311.1958.tb00158.xHoward Journal of Criminal Justice
In this study, we aim to investigate the origins of repopulated microglia in the retina. Interestingly, we find that repopulated retinal microglia are not derived from Nestin-positive progenitor cells. Instead, they have two origins: the center-emerging microglia are derived from residual microglia...
Blocking stress response in microglia reverses Alzheimer's symptoms in mice, researchers report. By JERUSALEM POST STAFF \ 12/25/2024 1:45:00 PM 'Gazafication': The terror threat in northern West Bank is growing - analysis Weapons are flowing to the West Bank and enabling the growing terroris...
the mysterious veil of epigenetic modification in AIDs has been gradually unraveled, and some progress has been made in utilizing it as indicators of diagnosis and disease activity. For example, the hypomethylated IFI44L promoter in diagnosing systematic lupus erythematosus (SLE). More recently, newly...
Microglia have been recently shown to manifest a very interesting phenotypical heterogeneity across different regions in the mammalian central nervous system (CNS). However, the underlying mechanism and functional meaning of this phenomenon are currently
Minocycline selectively inhibits M1 polarization of microglia. Cell Death Dis. 2013, 4, e525. [Google Scholar] [CrossRef] [PubMed] Garrido-Mesa, N.; Zarzuelo, A.; Galvez, J. What is behind the non-antibiotic properties of minocycline? Pharmacol. Res. 2013, 67, 18–30. [Google ...
The age-related decline in tissue regenerative capacity is largely due to the functional attrition of underlying stem cells [156]. SCs of different origins, such as HSCs [157], NSCs [158], or MDSPCs [159], have shown a decrease in cell cycle activity and differentiation courses with time....
The freshly produced ECM components may be secreted by reactive astrocytes, oligodendrocyte precursors, microglia/macrophages and eventually by meningeal cells. The lesion and consequent reactive processes induce a matrix accumulation that strongly resembles the juvenile-type of meshwork previously observed ...
Ginhoux F, Garel S (2018) The mysterious origins of microglia. Nat Neurosci 21:897–899 Ginhoux F, Greter M, Leboeuf M, Nandi S, See P, Gokhan S, Mehler MF, Conway SJ, Ng LG, Stanley ER, Samokhvalov IM, Merad M (2010) Fate mapping analysis reveals that adult microglia derive fro...
530—40)and Cell Discovery (2018,4(1):9)to decipher the origins of repopulated microglia in the brain and retina.These two studies,supported by the National Natural Science Foundation of China,were led by Dr.Peng Bo(彭勃)at Shenzhen Institutes of Advanced Technology,Chinese Academy of ...