Discusses the molecular mechanisms of peroxisome proliferator-activated receptor (PPAR) action and the involvement of PPAR in the etiology and treatment of several chronic diseases. Structure of PPAR; Physiological role of PPAR as lipid sensors and regulators of lipid metabolism; Pathophysiology of PPAR...
THE MECHANISMS OF ACTION OF PPARS. Discusses the molecular mechanisms of peroxisome proliferator-activated receptor (PPAR) action and the involvement of PPAR in the etiology and treatment of... Berger,Joel,Moller,... - 《Annual Review of Medicine》 被引量: 3148发表: 2002年 An overview on ...
The mechanisms of action of PPARs. Annu Rev Med 2002; 53: 409–435. 15 Zhu Y, Qi C, Korenberg JR, Chen XN, Noya D, Rao MS et al. Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPAR gamma) gene: alternative promoter use and different splicing yield ...
Nat Genet 26:76–80 Berger J, Moller DE (2002) The mechanisms of action of PPARs. Annu Rev Med 53:409–435 Bouchard C (1996) Genetic epidemiology, association, and sib-pair linkage: results from the Quebec Family Study. In: Bray GA, Ryan DH (eds) Molecular and genetic aspects of ...
Berger J, Moller DE (2002) The Mechanisms of action of PPARs. Annu Rev Med 53:409–435 Article CAS Google Scholar Botta M, Audano M, Sahebkar A, Sirtori CR, Mitro N et al (2018) PPAR agonists and metabolic syndrome: an established role? Int J Mol Sci 19:1197 Article PubMed ...
Moller The mechanisms of action of PPARs Annu Rev Med, 53 (2002), pp. 409-435 CrossrefView in ScopusGoogle Scholar [119] A. Sapone, J.M. Peters, S. Sakai, et al. The human peroxisome proliferator-activated receptor alpha gene: identification and functional characterization of two natural...
Moller The mechanisms of action of PPARs Annu. Rev. Med., 53 (2002), pp. 409-435 CrossrefView in ScopusGoogle Scholar [77] K.W. Chung, E.K. Lee, M.K. Lee, G.T. Oh, B.P. Yu, H.Y. Chung Impairment of PPARα and the fatty acid oxidation pathway aggravates renal fibrosis ...
Traditional pharmacologic approaches had identified several classes of xenobiotics that elicited characteristic biological effects in vivo but that lacked defined molecular mechanisms of action. Among these xenobiotics were the peroxisome proliferators, the thiazolidinediones (TZDs), and a se...
E. The mechanisms of action of PPARs. Annu Rev Med 53, 409–435, https://doi.org/10.1146/annurev.med.53.082901.104018 (2002). Article CAS PubMed Google Scholar Evans, R. M., Barish, G. D. & Wang, Y. X. PPARs and the complex journey to obesity. Nat Med 10, 355–361, ...
E. The mechanisms of action of PPARs. Annu Rev Med 53, 409–435, https://doi.org/10.1146/annurev.med.53.082901.104018 (2002). Article CAS PubMed Google Scholar Evans, R. M., Barish, G. D. & Wang, Y. X. PPARs and the complex journey to obesity. Nat Med 10, 355–361, ...