Repetitive DNA sequences playing critical roles in driving evolution, inducing variation, and regulating gene expression. In this review, we summarized the definition, arrangement, and structural characteristics of repeats. Besides, we introduced diverse biological functions of repeats and reviewed existing...
et al. A systematic evaluation of short tandem repeats in lipid candidate genes: riding on the SNP-wave. PLoS ONE 9, e102113 (2014). Article PubMed PubMed Central Google Scholar Levinson, G. & Gutman, G. A. Slipped-strand mispairing: a major mechanism for DNA sequence evolution. Mol...
6. For primates in particular, the tail is adapted to a range of environments, with implications for the style of locomotion of the animal11,12. The New World howler monkeys, for example, evolved a prehensile tail that helps with the grasping or holding of objects while occupying arboreal...
Here we examine the structure of the macronuclear DNA ofNyctotherus ovalis, a member of a third group of ciliates known as the heterotrichous ciliates.N. ovalislives in an anaerobic intestinal environment. It is of particular interest because it possesses hydrogenosomes that contain a genome [...
We chose odd lengths to prevent issues associated with searching for reverse complement sequences. Many of viral k-mer sequences could be identified in the human genome within relatively short edit distances when the length was set at 21 or 23 bases (Additional file 1; Table S2). Increasing ...
Good light can bring shape and depth to a photograph. In particular, low side-lighting or “glancing light” can be used to transform your landscape photographs and make them come to life. In Photo A (below), the feathery June grass, yellow flowers of hoary puccoon, and other ground folia...
does the orientation of tfbss matter? is it important for the binding and subsequent transcriptional induction or repression of the downstream gene, whether the tfbs is present in a particular orientation such that forward and reverse-complement orientations are distinguishable and have different ...
In particular, we show the relevance of the defectless pairing of 3′ terminals imposed by the polymerase in PCR selection. We also evaluate the selectivity afforded by the microRNA seed region, thus quantifying the extra contributions given by mechanisms beyond pairing statistics. Keywords: nucleic...
However, if their overproduction surpasses the antioxidant capacity of the cell, these radicals begin to oxidize protein and lipid cell elements, and inflict physical and chemical damage to the DNA molecule [1], resulting in modified bases, single and double-strand breaks, and DNA-DNA and DNA-...
The majority of the 5,156 predicted protein coding regions (3,501 or 68%) had lengths of less than 150 nt. It is likely that these EST sequences represent 5', or 3'- UTRs and predicted short coding regions are mere artifacts or represent very small proteins. Comparative genomics ...