Smith, AM and Dragunow, M (2014) The human side of microglia. Trends Neurosci 37:125-35. doi: 10.1016/j.tins.2013.12.001. PMID: 24388427Smith AM, Dragunow M: The human side of microglia. Trends Neurosci 2014, 37:125-135.Smith, A. M. & Dragunow, M. The human side of microglia...
The human side of microglia. Trends Neurosci. 37, 125–135 (2014). CAS PubMed Google Scholar Streit, W. J., Braak, H., Xue, Q.-S. & Bechmann, I. Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in ...
J. Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neurovascular and neuroinflammatory disease. Biochim. Biophys. Acta 1862, 442–451 (2016). Article CAS PubMed Google Scholar Smith, A. M. & Dragunow, M. The human side of microglia. Trends Neurosci. 37, 125–135 (2014...
A multispecies probiotic accelerates fear extinction and inhibits relapse in mice: Role of microglia. Neuropharmacology 2021, 193, 108613. [Google Scholar] [CrossRef] Chu, C.; Murdock, M.H.; Jing, D.; Won, T.H.; Chung, H.; Kressel, A.M.; Tsaava, T.; Addorisio, M.E.; Putzel...
To maintain retinal homeostasis, the retina is also protected by its own innate immune system composed of the microglia and the complement system. In case of an insult, microglia cells migrate to sites of damage, release pro-inflammatory cytokines and reactive oxygen species (ROS) to neutralize ...
(HSV-1) can activate microglia by increasing mitochondrial damage through defective mitophagy, while the microbial metabolite NAMO can inhibit microglia activation and HSV-1 induced herpes simplex encephalitis (HSE) progress by restoring NAD+ dependent mitophagy (Li et al.2022,2023). Trimethyl-5-...
Microglia, the resident macrophages of the central nervous system, rapidly activate in nearly all kinds of neurological diseases. These activated microglia
In the female gonads, the majority of immune cells are either Pre-PraM or PraM cells [2, 5, 18]. Research [2] has shown that yolk sac-derived macrophage precursors (YSdMPs) can differentiate into primitive macrophages (PraMs), microglia, or microglia-like cells during development. Notably,...
After the occurrence of ICH, the administration of ELP resulted in a decline in brain edema, an amelioration of neurological function, and a decrease in activated microglia. Following ICH, ELP reduced RhoA levels, phosphorylated serine-IRS1, while increasing phosphorylated tyrosine-IRS1 and p-Akt,...
As important immune cells, microglia undergo a series of alterations during aging that increase the susceptibility to brain dysfunctions. However, the longitudinal characteristics of microglia remain poorly understood. In this study, we mapped the transc