The Human Genome Project has revealed that there are probably about 20,000-25,000 'haploid' protein coding genes. The completed human sequence can now identify their locations. But only about 1.5% of the genome codes for proteins, while the rest consists of non-coding RNA genes, regulatory s...
To gain further insights into the gene function, we focused on about 208 human gene families, consisting of 4,614 genes [25, 26]. We asked about the multifractal genomic context for these gene families. The distributions obtained show three different multifractal behaviors (Figure 5B): low-skew...
2,3,4. The All of Us Research Program is a longitudinal cohort study aiming to enrol a diverse group of at least one million individuals across the USA to accelerate biomedical research and improve human health5,6. Here we describe the...
L1 is the only abundant and active LINE in the human genome, and the human genome contains an estimated 100,000 truncated and 4000 full-length L1 elements accounting for about 17% of the entire genome82. Since L1 correlations with disease and immunity by producing gene mutations, it has ...
Fn was identified in 63 samples according to its marker genes and the corresponding phylogenetic tree showed no correlation with patient age, tumor stage, and location (Supplementary Fig. 4a). No significant difference was observed in the Fn prevalence between oCRC and yCRC. Genome-wide sequence...
The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the...
Could Certain Genes Help You Slim Down? HealthDayOct. 11, 2024 Boys Treated With Gene Therapy for Rare Brain Disease Doing Well 6 Years Later HealthDayOct. 10, 2024 When a Child Has a Rare Disease It can be an odyssey just to get a diagnosis for a rare disease, so how can parents ...
As the "human genome project" study on the rapid development of the human whole genome sequencing has been completed, a large number of human genes have been found, human genome research access to large amounts of information, "Pharmacogenomics" came into being. Pharma ...
The prioritized genes of top 20 significant fibrosis-associated DMPs are labeled. b Single-nuclear RNA-seq UMAP of 223,438 human kidney cells. Each dot represents a cell, with color coding for the cell types: Endo_GC; endothelial cells of glomerular capillary tuft, Endo_peritubular; endothelial...
The gymnosperm Welwitschia mirabilis belongs to the ancient, enigmatic gnetophyte lineage. It is a unique desert plant with extreme longevity and two ever-elongating leaves. We present a chromosome-level assembly of its genome (6.8 Gb/1 C) together