Buckingham JC, Loxley HD, Christian HC, Philip JG (1996) Activation of the HPA axis by immune insults; roles and interactions of cytokines, eicosanoids, and glucocorticoids. Pharmacol Biochem Behav 54: 285–298 Article PubMed CAS Google Scholar Turnbull A, Rivier C (1999) Regulation of the ...
HPA axis:The HPA axis is part of the neuroendocrine system that plays a prominent role in regulating several important functions in the body, including stress response, metabolic function, immune system, cardiovascular system, and reproductive system. It is essentially a feedback system among the ...
Fulford AJ, Harbuz MS (2005) An introduction to the HPA axis. In: Steckler T, Kalin NH, Reul JMHM (Ed.). Handbook of stress and the brain. Part 1. P43-61. Amsterdam: Elsevier B.V.Fulford AJ, Harbuz MS. An introduction to the HPA axis. In: Hand- book of Stress and the ...
Who discovered the HPA axis?HPA Axis:The HPA axis is a cell signalling network which involves the hypothalamus region of the brain, the pituitary gland and the adrenal glands. It is responsible for the release of the stress hormones cortisol and adrenaline....
In contrast, chronic alcohol use leads to dysregulation of the HPA axis and a sustained elevation of plasma cortisol30. Cortisol causes multiple cellular effects in different tissues by binding to a ubiquitously distributed intracellular glucocorticoid receptor (GR)31. Many studies have addressed the ...
In addition to glucocorticoids, during stimulation of the HPA axis, the catecholamine hormones epinephrine and norepinephrine are released from the adrenal medulla42,43. Adrenergic receptors (ARs) for these hormones are located on the surface of immune cells. Many studies have shown that α- and β...
The interface of stress and the HPA Axis in behavioural phenotypes of Mental Illness. Curr Top Behav Neurosci. 2014;18:13–24. Article PubMed Google Scholar Buhle JT, Silvers JA, Wager TD, Lopez R, Onyemekwu C, Kober H, et al. Cognitive reappraisal of emotion: a meta-analysis of ...
Two experiments were conducted to measure both the psychological and physiological effects of touching on the HPA axis related parts of the body. HPA stands for the hypothalamus, pituitary, and adrenal. One experiment was conducted with a group of healthy experiment participants, and another was wit...
Seizure-induced activation of the HPA axis results in future seizure susceptibility which can be blocked by treatment with an NKCC1 inhibitor, bumetanide, or blocking the CRH signaling with Antalarmin. These data suggest that compromised GABAergic control of CRH neurons following an initial seizure ...
HPA Axis: The Hypothalamic-pituitary-adrenal (HPA) axis is a part of the endocrine system that modulates primarily stress responses as well as other body processes, including digestion and the immune system. The hypothalamus and pituitary glands are both in the brain, while the adrenal (suprarenal...