Chemical space is a nebulous term used in various ways, but pertinent to drug discovery, it is the classification of molecules in terms of their physicochemical make-up, such as size, shape, lipophilicity, charge and hydrogen-bonding potential, which together can be used to describe the chemical...
1.a class of individuals having some common characteristics or qualities; distinct sort or kind. 2.the major subdivision of a genus or subgenus, regarded as the basic category of biological classification, composed of related individuals that resemble one another, are able to breed among themselves...
The laurel family within the Magnoliids has attracted attentions owing to its scents, variable inflorescences, and controversial phylogenetic position. Here, we present a chromosome-level assembly of theLitsea cubebagenome, together with low-coverage genomic and transcriptomic data for many other Laurace...
Cannabis sativa, a dioecious plant that has been cultivated worldwide for thousands of years, is known for its secondary metabolites, especially cannabinoids, which possess several medicinal effects. In this study, we investigated the autopolyploidization effects on the biosynthesis and accumulation of ...
Journal of Biological Chemistry, Volume 295, Issue 52, 2020, pp. 18328-18342 Shuhei Suzuki,…, Chifumi Kitanaka View PDF Osteoclast-derived apoptotic bodies inhibit naive CD8+ T cell activation via Siglec15, promoting breast cancer secondary metastasis Cell Reports Medicine, Volume 4, Issue 9, ...
The LINE type TE classification retained nearly all of the classes (26.39%, ~ 629 Mb; Table S9). Comparative genomic analysis To distinguish gene families, we performed an all-vs-all comparison between T. leucocephalus, T. francoisi, and 14 closely related species, namely Nomascus ...
Table 1. Classification of eccDNA. Name of the eccDNASizeFrequencyCharacteristicFunctionMain Refs SpcDNA 100 bp- 10 kb More frequent in unstable cells Homologous to repetitive chromosomal sequences; byproducts or intermediates of gene rearrangement Initiation or enhancement of genomic instability [21,22...
Secondary metabolites have shown to possess various biological effects, which provide the scientific base for the use of herbs in the traditional medicine in many ancient communities. They have been described as antibiotic, antifungal and antiviral and therefore are able to protect plants from pathogens...
Wellcome Centre for Cell Biology and Institute of Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, EH9 3BF, Scotland, UK Emily R. Fowler AstraZeneca, Oncology R&D, Cambridge, UK Hazel J. Jones Corresponding author ...
E. Change in the rate of biological aging in response to caloric restriction: CALERIE Biobank Analysis. J. Gerontol. A Biol. Sci. Med. Sci. 73, 4–10 (2017). Article PubMed PubMed Central Google Scholar Leclerc, E. et al. The effect of caloric restriction on working memory in ...