Ferroptosis is a non-apoptotic cell death mechanism characterized by iron-dependent membrane lipid peroxidation. Here, we review what is known about the cellular mechanisms mediating the execution and regulation of ferroptosis. We first consider how the accumulation of membrane lipid peroxides leads to ...
Throughout this Review, we highlight open questions and areas in which progress is needed to better understand the cell biology of ferroptosis.doi:10.1038/s41580-024-00703-5Scott J. Dixonhttps://ror.org/00f54p054grid.168010.e0000 0004 1936 8956Department of BiologyStanford University Stanford...
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The cell biology of ferroptosis 铁下垂的细胞生物学研究 相关领域 细胞器内质网GPX4线粒体生物程序性细胞死亡过氧化物酶体细胞生物学脂质过氧化脂质代谢脂滴细胞细胞凋亡化学生物化学氧化应激受体超氧化物歧化酶谷胱甘肽过氧化物酶 网址 https://doi.org/10.1038/s41580-024-00703-5 ...
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Ferroptosis is an iron-dependent form of non-apoptotic cell death characterized by excessive lipid peroxidation and associated with a plethora of pathological conditions in the liver. Emerging evidence supports the notion that dysregulated metabolic path
Ferroptosis is a newly recognised type of regulated cell death (RCD) characterised by iron-dependent accumulation of lipid peroxidation. It is significantly distinct from other RCDs at the morphological, biochemical, and genetic levels. Recent reports ha
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