The chemistry and biology of ferroptosis Cell Chem Biol (2020) H. Wang et al. Emerging mechanisms and targeted therapy of ferroptosis in cancer Mol. Ther. (2021) Y. Su et al. Ferroptosis, a novel pharmacological
The chemistry and biology of ferroptosis. Cell Chem. Biol. 27, 365–375 (2020). Article CAS PubMed PubMed Central Google Scholar Stockwell, B. R., Jiang, X. & Gu, W. Emerging mechanisms and disease relevance of ferroptosis. Trends Cell Biol. 30, 478–490 (2020). Article CAS Pub...
Jiang The chemistry and biology of ferroptosis Cell Chem Biol, 27 (4) (2020), pp. 365-375, 10.1016/j.chembiol.2020.03.013 View PDFView articleView in ScopusGoogle Scholar [34] M. Conrad, V.E. Kagan, H. Bayir, G.C. Pagnussat, B. Head, M.G. Traber, B.R. Stockwell Regulation...
Ferroptosis: a cell death connecting oxidative stress, inflammation and cardiovascular diseases ArticleOpen access26 July 2021 Introduction Various forms of regulated cell death, such as apoptosis, necroptosis, pyroptosis and autophagy, have been implicated in the pathogenesis of cardiovascular diseases1. In...
Table 2 Kinds of ferroptosis inducers Full size table However, a detailed explanation regarding the molecular pathway (with special emphasis on current/ongoing research) has not been established successfully. Furthermore, from chemistry perspectives, this review presented adequate knowledge on designing of...
computational chemistry, high-throughput screening (HTS), drug design and chemical synthesis, as well as pharmacokinetics and pharmacodynamics studies (PK/PD), a comprehensive approach is emerging for new drug research and development [208,219,220]. However, due to the conceptual and methodological ...
Powell CR, Dillon KM, Matson JB (2018) A review of hydro- gen sulfide (H2S) donors: chemistry and potential therapeutic applications. Biochem Pharmacol 149:110–123. https://doi.org/ 10.1016/j.bcp.2017.11.014 144. Chen Y, Teng X, Hu Z et al (...
A daily digest of scientific microbiome papers, by the MD team. Founded by Elisabeth Bik, microbiome and science integrity consultant. Twitter: @microbiomdigest
doi:10.1074/jbc.RA119.009548Hironari NishizawaMitsuyo MatsumotoTomohiko ShindoDaisuke SaigusaHiroki KatoKatsushi SuzukiMasaki SatoYusho IshiiHiroaki ShimokawaKazuhiko IgarashiAmerican Society for Biochemistry and Molecular BiologyThe Journal of Biological Chemistry...
Chemistry and biology of ophiobolin A and its congeners. Bioorg. Med. Chem. Lett. 29, 859–869. https://doi.org/10.1016/j.bmcl.2019.02.007 (2019). Article PubMed CAS Google Scholar Bencsik, O. et al. Ophiobolin A from bipolaris oryzae perturbs motility and membrane integrities of ...