2005. Bordetella pertussis, the causative agent of whooping cough, evolved from a distinct, human-associated lineage of Bordetella bronchiseptica. PLoS Pathog. 1:e45. http://dx.doi.org/10.1371/journal .ppat.0010045.Diavatopoulos, D. A., Cummings, C. A., Schouls, L. M., Brinig, M. ...
This pain is usually sharp and worsens when taking a deep breath and is known as pleuritic pain or pleurisy. In other cases of pneumonia, depending on the causative organism, there can be a slow onset of symptoms. A worsening cough, headaches, and muscle aches may be the only symptoms. ...
The story that his discovery of attenuation — using the causative organ- ism of chicken cholera, now known as Pasteurella multocida — was an accident has gained currency .13,14 That story is disputed but, whether by accident or premeditation, Pasteur learned that he could attenuate a ...
Bordetella bronchiseptica is a respiratory pathogen that is closely related to Bordetella pertussis and Bordetella parapertussis, the causative agents of whooping cough in humans [9, 10]. B. bronchiseptica causes a range of diseases in various mammals that can be chronic, difficult to completely eradi...
Related to bordetella:Bordetella pertussis,Kennel cough bor·de·tel·la (bôr′də-tĕl′ə) n. Any of various small, gram-negative coccobacilli of the genusBordetella,some of which are pathogenic in the human respiratory tract. It includesB. pertussis,the causative agent of whooping cou...
Tetanus is caused by the deposition of the spores of the causative agent into a wound in which necrotic tissue is present (anaerobic conditions). Deposition may occur with soil or a piece of fabric or wood harboring the spores. The disease is common among troops during wartime. It may also...
Diagnosis is typically made based on clinical signs and symptoms, without laboratory testing to determine the specific causative agent. Antibiotics are frequently prescribed for the treatment of AOM. High-doseamoxicillinis the first-line drug, but with increasing resistance concerns, macrolides andcephalos...
tuberculosis, the causative organism of tuber- culosis, we illustrate how concepts of polypharmacology can be understood and applied in a systematic manner by adopting a struc- tural proteomics approach that analyses binding sites at a genome scale and identifies promising drug candidates from approved...
Chlamydia is a sexually transmitted disease. In many infected people there are no visible signs of infection but this does not prevent them from passing the disease on to their sexual partners.Answer and Explanation: The causative agent of chlamydia is a bacteria which is called Chlamydia ...
which recruits host proteins to potentiate oncogenic signalling via a long IDR20. Another illustrative example is the effector CyaA ofBordetella pertussis, the causative agent of whooping cough that interacts with host calmodulin via a disordered stretch of 75 amino acid residues21. Other less-ordered...