Bordetella pertussis causes whooping cough, a severe respiratory tract infection in infants and children, and also infects adults. Studies in murine models have shown that innate immune mechanisms involving dendritic cells, macrophages, neutrophils, natural killer cells, and antimicrobial peptides help ...
nature publishing group See COMMENTARY page XX REVIEW Immunity to the respiratory pathogen Bordetella pertussis R Higgs1, SC Higgins2, PJ Ross2 and KHG Mills1,2 Bordetella pertussis causes whooping cough, a severe respiratory tract infection in infants and children, and also infects adults. ...
To gain insight into the structure of N-Tir’s dimer core, we turned to AlphaFold-2 (AF-2)52and Flexible Meccano (FM)53to create a structural ensemble model of the NS-Tir dimer (Fig.3a) consistent with SAXS data (Fig.3b). AF-2 is an AI-based method that predicts a protein’s 3...
To gain insight into the structure of N-Tir’s dimer core, we turned to AlphaFold-2 (AF-2)52and Flexible Meccano (FM)53to create a structural ensemble model of the NS-Tir dimer (Fig.3a) consistent with SAXS data (Fig.3b). AF-2 is an AI-based method that predicts a protein’s 3...
come fromPseudomonas,Escherichia,andMycobacterium, which are widespread and persistent in the environment [79]. In addition, Cya is worth noting as an essential unit ofBacillus anthracisvirulence that causes anthrax and may lead to mammalian death [80]. Known homologs in the GenBank database of...
including whooping cough, tetanus and cardiovascular diseases. Also, today, extracts made from thecentipedeare being assessed for theirpotential to fight cancerand to serve as apotent pain killer. But rarely are raw wild centipedes consumed to treat ailments. Lingli said the patients that are the...
Whooping coughBordetella pertussis is the causative agent of pertussis, which mainly affects unvaccinated children, while Bordetella parapertussis causes a disease presenting clinical characteristics that are indistinguishable from whooping cough. Despite high vaccination coverage, pertussis remains a public ...