1985. The role of ATP hydrolysis in the break- down of proteins and peptides by protease La from Escherichia coli. J Biol Chem 260:12029-12034.Goldberg AL, Waxman L. 1985. The role of ATP hydrolysis in the breakdown of proteins and peptides by protease La from Escherichia coli. J ...
Analysis of Walker motif B mutants suggests that ATP hydrolysis at the two ABC domains is strictly coordinated and is essential for the function of Uup in vivo. 展开 关键词: Hydrolysis Essential Function ATPbinding Cassette Excision Transposons ...
The results envisage a minimal model of three conformational states of MutS as reflected in: (i) a specific and highly stable MutS–mismatch complex in the absence of a nucleotide; (ii) a specific but less stable complex in the presence of ATP hydrolysis; and (iii) an irreversibly ...
Figure 1. Key properties of ATP and nucleic acids for modulating LLPS of FUS, TDP-43, and SARS-CoV-2 nucleocapsid proteins. (a) ATP has unique structural properties and thus may act as (I) energy currency by hydrolysis of high-energy bonds; (II) a biological hydrotrope with the presence...
S. The full-length structure of Thermus scotoductus OLD defines the ATP hydrolysis properties and catalytic mechanism of class 1 OLD family nucleases. Nucleic Acids Res. 48, 2762–2776 (2020). Article CAS PubMed PubMed Central Google Scholar Cheng, R. et al. Prokaryotic Gabija complex ...
Replication normally initiates from the origin, where DNA helicase separates DNA double helix and creates the replication fork utilizing energy from ATP hydrolysis3. DNA primase recognizes single-stranded DNA (ssDNA) to synthesize RNA oligonucleotides used as primers to initiate DNA replication. DNA ...
These cysteine residues were then used as the site of attachment of MBP. The results indicate that subunit H and subunit F (one of the rotor subunits) are proximal in the free V1 domain but not in the intact V1V0, supporting the hypothesis that subunit H inhibits ATP hydrolysis in V1...
The chemical mechanism of ATP hydrolysis by nitrogenase is discussed in terms of results from isotopic exchange studies using [18O4]-Pi, b,g-[18O]-ATP, and g-[18O4]-ATP as probes of reversibility (ATP = ADP + Pi) and of the freedom of rotation around the O-Pb bond in enzyme-...
摘要: Publication » Corrigendum to “ATP hydrolysis at one of the two sites in ABC transporters initiates transport related conformational transitions” [Biochim. Biophys. Acta 1808 (2011) 2954–2964].关键词: constraint-based programming control convex optimization iTaSC ...
Copper transporting P-type (P1B-1-) ATPases are essential for cellular homeostasis. Nonetheless, the E1-E1P-E2P-E2 states mechanism of P1B-1-ATPases remains poorly understood. In particular, the role of the intrinsic metal binding domains (MBDs) is enigm