one of two or more alternative forms of a gene occupying the same position on matching chromosomes: an individual normally has two alleles for each trait, one from either parent. [1930–35; < GermanAllel,appar. as shortening of German equivalents ofallelomorphorallelomorphic gene] ...
An initial assessment considers coverage of each individual and evidence for contamination, updating annotations as needed. In addition, we manually curate the genotypes to check that the data from each individual has sensible population genetic properties, by looking for potential outliers based on ADMI...
We assume a selfish genetic element that can gain a propagation advantage through distorting some trait of the organism (‘trait distorter’). This trait distortion only benefits alleles at a subset of loci within the genome—Leigh termed this subset of loci a ‘cabal’30. The rest of the ...
organism, being - a living thing that has (or can develop) the ability to act or function independently dihybrid - a hybrid produced by parents that differ only at two gene loci that have two alleles each monohybrid - a hybrid produced by crossing parents that are homozygous except for a ...
While it is hypothesized that EMA alleles within T. equi or T. haneyi n. sp. are less divergent than the orthologues, data is required from within each species to confirm this. Download: Download high-res image (194KB) Download: Download full-size image Fig. 3. Phylogenetic and synteny ...
Figure 3. Boxplot displaying (a) proportion of unique alleles, (b) the mixture proportion and (c) 𝑅𝐹𝑈 RFU¯ values corresponding to the wrapper (C1pack) and the handler (C2tape) of the tape. Three samples had no profiling results and for an additional three samples only four...
Genes and alleles are genetic sequences, and both determine biological traits. So, what makes them different?
Several previous studies have identified a potential role that the gut microbiome can play in autism spectrum disorder (ASD) in children, but little is known about how variations in the virome may be involved in ASD. We aimed to understand the changes in
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T-lineage acute lymphoblastic leukaemia (T-ALL) is a high-risk tumour1 that has eluded comprehensive genomic characterization, which is partly due to the high frequency of noncoding genomic alterations that result in oncogene deregulation2,3. Here we report an integrated analysis of genome and tra...