Previously DRB1*1406 was described as a characteristic allele of some Native American or northeast Asian ethnic groups, and DRB1*1106 had been found in only two Singapore Chinese and one Korean. Principal component analysis of various populations based on HLA class II allele frequencies places the ...
The probability that a mutant allele is transmitted from an individual who carries the allele (F1) to its offspring in a given generation (Fi) can be given as follows: PðXXijXX1Þ ¼ PðXXi; XXði-1ÞjXX1Þ þ PðXXi; XXði-1ÞjXX1Þ þ PðXXi; XYði...
Methods: We evaluated the HLA-B and HLA-DRB1 distribution among 160 renal recipients: 132 with hyperuricemia (Group 1) and 28 free of it (Group 2) as well as 381 ethnic-specific Mexican- mestizo population historic controls. The HLA alleles were assessed by PCR-SSP and the HLA allele gene...
When both alleles are the same the individual is described as being a HOMOZYGOTE; when each allele is different the individual is a HETEROZYGOTE. The number of allelic forms of a gene can be many (MULTIPLE ALLELISM), each form having a slightly different sequence of DNA bases but with the ...
Many of the variations are residues that are in the peptide binding pockets and may affect peptide binding capabilities as well as T-cell recognition. Therefore, identification of these novel alleles may have important implications in selection of unrelated donor-recipient pairs in allogenic bone ...
(Hymenoptera: Braconidae), the first species in which sex determination was shown to be regulated by a series of alleles segregating at a single locus (Whiting, 1943). Our goals were to (i) determine whether within-population sex allele diversity is so low as to introduce a strong sex ...
HLA-E may act as a sentinel of the cell; if classical class I and HLA-G are being expressed, HLA-E molecules may reach the cell surface and inhibit the lysis by NK cells. Most findings are consistent with the hypothesis that HLA-E and -G proteins may be tolerogenic molecules at ...
seeking may simply be a chance event, but the possibility that the present results represent a false negative should be viewed in the context of the absence of previous data showing an association between the DRD4*7R allele and diagnoses associated with high novelty seeking, such as alcoholism....
BackgroundVariant RHD alleles and anti-D immunization are more prevalent in Africans as compared to Europeans. The aberrant RHD alleles of the DAU (in German: "D Afrikanischen Ursprungs") cluster are considered to be one of the major cau... S Meyer,C Portmann,BM Frey,... 被引量: 0...
aMelanin contents were spectrometrically determined as described previously (Choi et al., 2007) except for the following modifications:five zebrafish larvae, at 72 hpf, were used per measurement, and pellets were dissolved in 0.2 ml of 1 N NaOH. Measurements were made in polystyrene 96-well fla...