Review Human Th1 and Th2 Cells: Functional Properties, Regulation of Development and Role in Autoimmunity[J] . Marco De Carli,Mario M. D’elios,Gianna Zancuoghi,Sergio Romagnani,Gianfranco Del Prete.Autoimmunity . 1994 (4)De Carli M.Human Th1 and Th2 CellS:functional properties,regulation of...
其中IL-4起中枢调节作用,诱导Ⅱ型细胞毒性T细胞(Tc2)和Ⅱ型固有淋巴样细胞(innate lymphoid cells 2,ILC2)的发展,促进B细胞产生IgE,使肥大细胞和嗜碱性粒细胞脱颗粒,释放炎症介质。另外,还有一个途径是上述警告信号绕开IgE,直接激活ILC2,其与Th2相对应,...
In this review, we focus on the CD4+ Th2 cells and their products as targets for the development of new drugs to add to the current armamentarium as adjuncts or as potential stand-alone treatments for allergic asthma. We argue that in early disease, the reduction or elimination of allergen...
TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties Annu Rev Immunol. 1989;7:145-73. Review TR Mosmann,RL Coffman - 《Annual Review of Immunology》 被引量: 1.7万发表: 1989年 Biology of human T H 1 and T H 2 cells Evidence is ...
Th2 cells produce a set of cytokines including IL-4 IL-5, IL-10, and IL-13 [12,14]. Th2 responses are associated with humoral immunity and protection against intestinal helminthes. Moreover, Th2 differentiation is regulated by GATA-3 [13]. View article Review article Autoimmunity * ...
This review will focus on the role of Th cells in the inflammatory process involved in allergic disease, diabetes, infectious disease, rheumatoid arthritis, heart disease, multiple sclerosis and cancer. In the area of autoimmunity, in particular, a basic understanding of Th cells and cytokines has...
Th2 Cells ⚠ WARNING: This product can expose you to chemicals including formaldehyde and methanol, which are known to the State of California to cause cancer and reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov.Related Products All Produc...
4、ve ligands for P- and E-selectin ,IL-18R, IL-12R2,CC chemokine receptor (CCR5) were shown to be dominantly expressed on Th1 cells,whereas expression of CD30,ST2L,CRTH2,CCR3,CCR4 was reported to be preferential to Th2 cells. In this review, several surface molecules were mainly dis...
Regulatory Status RUO Other Names IFN-γ, IL-5, TNF-α, IL-2, IL-6, IL-4, IL-10, IL-13 Ave. Rating Submit a Review Product Citations 2publications Cat #SizePriceQuantitySave 741054100 tests$1174 Description T helper (Th) cells play important roles in regulating immune responses. They...
This review will focus on the research progress concerning Th2 and ILC2 cells in allergic pulmonary inflam‐ mation as well as targeted therapy for allergic diseases. [Key words] Th2;ILC2;Allergic pulmonary inflammation 经过多年研究,目前免疫学理论得到了极大的 发展,各种免疫细胞亚型被相继鉴定出来,...