TGF-beta Signaling Pathway (KEGG) showing rat P0-Ovary genes affected by AMH treatment.Eric, E. NilssonRyan, SchindlerMarina, I. SavenkovaMichael, K. Skinner
同时将所有差异性表达基因导入Genespring 软件后,得出GeneOntologyanalysis和Pathwayanalysis结果。 2结果 按照KEGG通路分类方法,TGF—B信号通路表达在转化前期与同代龄对照组细胞相比无统 计学差异,而在转化细胞与对照细胞相比存在统计学差异(p<0.05)。 3讨论 本课题组前期研究显示b1,GMA诱导第30代人支气管上皮(16HBE...
Next, KEGG analysis suggested that CCNA1 may suppress osteoblast differentiation via several signaling pathway including TGF-beta signaling pathway which plays an important role in maintaining bone homeostasis [43, 44]. Interestingly, BMP2, one of the evaluation marker of osteoblast differentiation, was...
Table 1 Regulation of putative candidate genes and corresponding KEGG numbers for size regulation in polyps with INSR-KD or FoxO-KD and after temperature shift The enrichment of DE genes for extracellular components of TGF-β signaling in the FoxO-KD animals clearly points to a role of this p...
In addition, 267 genes were mapped to the KEGG pathways and 14 pathways with more than nine differentially expressed genes were identified. In our model, Smad signaling was not the TGF beta 1 action effector; instead, the engagement of RAS/MAPK signaling pathway seems mainly to regulate genes ...
TGF-beta Signaling Pathway KEGGConnexin 43Transforming Growth Factor betaheart fibroblastFibroblastMyofibroblastsHeartIndividualized InstructionDifferentiation and activation of fibroblasts into myofibroblasts which express alpha-smooth muscle actin (alpha-SMA) are essential for wound healing and tissue repair. ...
TGF-beta Signaling Pathway KEGGSLC22A3 geneImmunodeficiencyITK genetransforming growth factor beta receptorTransforming Growth Factor betaEmergency Medical TechniciansAttenuationCancer of PancreasRNA InterferencePrevious studies in our laboratory identified that 3-deazaneplanocin A (DZNep), a carbocyclic adenosine...
KEGG pathway analysis of the predicted miRNA targets further indicated that these differentially expressed miRNAs are involved in various signaling pathways, such as Wnt, MAPK, and TGF-beta signaling, which might be involved in follicular development. These results provide valuable information on the ...
Then, Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis demonstrated that genes negatively associated with CCNA1 were enriched in the TGF-beta signaling pathway. Inhibitor of TGF-beta signaling pathway partly reversed osteogenesis induced by suppressed CCNA1. Furthermore, suppressed CCNA1 relieved...
Carcinoembryonic antigen (CEA) is widely used as a prognostic clinical marker of metastasis, and the TGF-β signaling pathway is significantly enriched in CEA-induced colorectal liver metastases (CRLM) according to the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis [33]. In a ...