New insights into TGF-beta/Smad signaling in tissue fibrosis. Chem Biol Interact 2018; 292: 76-83.Feng, Ya-Long,Chen,etc.New insights into TGF-beta/Smad signaling in tissue fibrosis[J].2018,292.ten Dijke P, Hill CS: New insights into TGF-beta-Smad signalling. Trends Biochem Sci 2004;...
TGF-[beta]-induced fibrosis and SMAD signaling: oligo decoys as natural therapeutics for inhibition of tissue fibrosis and scarring [corrected] [published erratum appears in WOUND REPAIR REGENERATION 2008 Jul-Aug;16(4):582] doi:10.1111/j.1524-475x.2007.00226....
Conversely, members of both miR-29 and miR-200 families are negatively regulated by TGF-尾/Smad3 and play a protective role in renal fibrosis by ... L Hui,C Arthur,X Yu - 《International Journal of Nephrology & Renovascular Disease》 被引量: 122发表: 2013年 Etiopathology of chronic tubul...
Shensong Yangxin Capsule prevents diabetic myocardial fibrosis by inhibiting TGF-β1Smad signaling 热度: 增生性瘢痕TGFβ1Smad信号转导通路的研究 热度: TGF-β1-Smad信号通路在肝纤维化中的作用机制及中医药调控研究进展 热度: 相关推荐 2014年6月1日第6期 No.61June2014 中医学报 CHINAJOURNALOF...
Activationof the canonical Wnt pathway stimulates fibroblasts in vitro and induces fibrosis in vivo.Transgenic overexpression of Dickkopf-1 ameliorates skin fibrosis induced by constitutivelyactive TGF-beta receptor type I signalling and also prevents fibrosis in other TGF-beta-dependentanimal models. ...
Transforming growth factor beta (TGF-β) is a potent pleiotropic polypeptide cytokine, with a complex and context dependent control of its activation, signaling and effector functions. This cytokine is pivotal in the regulation of immunological responses, tumor initiation and development, stromal homeosta...
3.Pterostilbene alleviates fructose-induced renal fibrosis by suppressing TGF-beta 1/TGF-beta type I receptor/Smads signaling in proximal tubular epithelial cells and spring 机译:活体通过抑制近端管状上皮细胞中的TGF-β1/ TGF-β型I受体/ Smads信号传导来减轻果糖诱导的肾纤维化 Gu Ting-Ting ,Chen ...
TGF-beta-induced SMAD signaling and gene regulation: consequences for extracellular matrix remodeling and wound healing. Members of the transforming growth factor-尾 (TGF-尾) superfamily are pleiotropic cytokines that have the ability to regulate numerous cell functions, incl... M Schiller,D Javelaud...
and extracellular matrix remodeling. Generally, signaling is initiated with the phosphorylation of the cytoplasmic Smad signaling molecules, which results in their translocation to the nucleus where they modulate transcription. TGF-βs are often overexpressed in many disease states such as fibrosis, inflam...
Focuses on a study that identified two putative p53 protein-binding sites in the promoter of a gene encoding PTGF-beta, a type beta transforming growth factor superfamily member. Efforts to understand p53 signaling pathways and mechanism of action; Methodology of the study; Results and discussion;...