1mL(10mM)|2mg|5mg|10mg|50mg|100mg|200mg发货周期:1～3天产品价格:询价本产品仅可用于科研实验,严禁用于其他非科研用途!LY2109761是一种选择性的TGF-β receptor type I/II双重抑制剂,Ki值分别为38nM和300nM。注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!CAS号:700874-71-1纯度:99.34%分子式:...
代替呼喊空口号,它是更有意义的跟需要中的孩子赠予书和运动货物。[translate] aa significant cluster of voxels voxels重大群[translate] aIn the United States , you can 在美国,您能[translate] ato compare their activity to a specific TGF-b receptor Type II inhibitor 正在翻译,请等待...[translate]...
However, the underlying mechanisms of resistance to SHP2 inhibition remain unknown. The E3 ligase SMURF2 limits TGFβ activity by ubiquitinating and targeting the TGFβ receptor for proteosome degradation. Using a functional RNAi screen targeting all known phosphatases, we identify that the tyrosine ...
查看TGF-β Receptor 亚型特异性产品: 查看所有亚型 ALK1ALK2ALK3ALK4ALK5ALK6ALK7TGFβR2ACVR2AACVR2B 生物活性 纯度& 产品资料 参考文献 生物活性 BIO-013077-01 is a pyrazoleTGF-βinhibitor[1]. 体外研究 (In Vitro) A wide range of cellular functions such as cell proliferation, differentiation, adh...
Radiosensitive ST3GAL5: Sialytransferase 5, GM3 synthase; TCGA: The Cancer Genome Atlas TGFBR1: Transforming growth factor beta receptor I TGFBR2: Transforming growth factor beta receptor II TGFBRs: Transforming growth factor beta receptors References...
另有研究表明在缺失TGF-β信号通路所依赖的TGF-β receptor I-III,以及缺少smad1或smad5的小鼠中,普遍会出现血管黑内皮细胞的缺陷。由此可见依赖于smad和TGF-β信号通路异常一定程度上可以通过血供的加强,促进肿瘤的发生发展。 早在19世纪苏格...
Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin ...
SB-431542 是一种有效,选择性的ALK5抑制剂,IC50值为 94 nM;同时也是转化生长因子 β 受体 (TGF-β Receptor) 抑制剂。 MCE 的所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务 生产商:MedChemExpress(MCE) 分子式:C22H16N4O3 分子量:384.39 ...
Optimization of a dihydropyrrolopyrazole series of transforming growth factor-beta type I receptor kinase domain inhibitors: discovery of an orally bioavailable transforming growth factor-beta receptor type I inhibitor as antitumor agent. (2008) J Med Chem. 51(7):2302-6. 2. Melisi D, et al. ...
另有研究表明在缺失TGF-β信号通路所依赖的TGF-β receptor I-III,以及缺少smad1或smad5的小鼠中,普遍会出现血管黑内皮细胞的缺陷。由此可见依赖于smad和TGF-β信号通路异常一定程度上可以通过血供的加强,促进肿瘤的发生发展。 早在19世纪苏格兰作家Robert Louis Stevenson就利用了人类原始的恐惧创作出了《化身博士》...