Interestingly, ELF, a beta-spectrin and a downstream adaptor protein of TGF-beta signaling, modulates STAT3 function. Overexpression of ELF inhibits the transcriptional activity of STAT3 by two folds as compared to control vector in hepatocellular carcinoma cell line. We conclude thatTGF-beta pathway...
which occurs when patients receive iodinated contrast after an imaging study such as a computed tomographic or angiogram1,2. This results in impaired kidney function and 30% of the patients may require renal replacement therapy or alternative support until the kidney function improves...
IL-6 and oncostatin M (OSM) belong to the same family of cytokines; their cell-surface receptors share the signal-transducing subunit gp130 and induce intracellular signaling through STAT3; both are well known for their profibrotic regulation in cell culture and in vivo; and blockade of these ...
机译:乙型肝炎病毒X蛋白通过激活JAK2 / STAT3信号通路调节人肾近端肾小管上皮细胞的凋亡 PING HE ,DAN ZHANG ,HONG LI -1 7.Shenning II Decoction Inhibits Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells via Regulation of Wnt/iβ/i-Catenin Signaling and spring 机译:Shenning II...
Activin Receptors - Products by Molelcule Activin RIA/ALK-2Activin RIB/ALK-4Activin RIIAActivin RIIA/BActivin RIIB Activin Family Modulators - Products by Molecule FollistatinFollistatin-like 1/FSTL1Follistatin-like 4/FSTL4Follistatin-like 5/FSTL5Follistatin-related Gene Protein/FLRGNOMO ...
Effect of TLR4 on the growth of siha human cervical cancer cells via the MyD88-TRAF6-TAK1 and NF-κb-cyclin D1-STAT3 signaling pathways The present study aimed to investigate the effect of Toll‑like receptor 4 (TLR4) on SiHa human cervical cancer cells and its potential molecular biolog...
Alantolactone 是一种STAT3的选择性抑制剂,可诱导癌症相关的凋亡,具有抗肿瘤活性。 Apoptosis ¥ 194 现货 规格 数量 客户已引用 选择批次: 浓度:3.03 mg/mL 纯度:SDS-PAGE:95% SEC-HPLC:95% 联系我们获取更多批次信息 资源下载 DataSheetSDSCOA产品操作手册 ...
Alantolactone 是一种STAT3的选择性抑制剂,可诱导癌症相关的凋亡,具有抗肿瘤活性。 Apoptosis ¥ 194 现货 规格 数量 客户已引用 "Vactosertib"的相关化合物库 膜蛋白靶向化合物库 Membrane Protein-targeted Compound Library L15204175 化合物 获取报价
Dahéron, L., Opitz, S.L., Zaehres, H., et al., LIF/STAT3 Signaling Fails to Maintain Self-Renewal of Human Embryonic Stem Cells, Stem Cells, 2004, vol. 22, pp. 770–778.PubMedCrossRef Dreesen, O. and Brivanlou, A.H., Signaling Pathways in Cancer and Embryonic Stem Cells, St...
Alantolactone 是一种STAT3的选择性抑制剂,可诱导癌症相关的凋亡,具有抗肿瘤活性。 Apoptosis ¥ 194 现货 规格 数量 客户已引用 "BMS986260"的相关化合物库 抗纤维化化合物库 Anti-Fibrosis Compound Library L98101800 化合物 获取报价 抗结直肠癌化合物库 ...