TGF-Beta/EGFR autocrine cross-talk affects EMT process and migration in 3D tissue-engeneered model of pancreatic ductal adenocarcinomaProceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Doublecortin-like kinase 1 (DCLK1) is overexpressed and marks a population of tumor-...
EGFR/NEDD9/TGF-BETA INTERACTOME AND METHODS OF USE THEREOF FOR THE IDENTIFICATION OF AGENTS HAVING EFFICACY IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERSEGFR/NEDD9/TGF-BETA INTERACTOME AND METHODS OF USE THEREOF FOR THE IDENTIFICATION OF AGENTS HAVING EFFICACY IN THE TREATMENT OF HYPERPROLIFERATIVE ...
Maximal immediate-early PAI-1 induction upon exposure to TGF-beta1 required EGFR, p21ras, MEK and pp60(c-src) signaling as pharmacologic or dominant-negative inhibition of any of the four intermediates (EGFR, p21ras, MEK, pp60(c-src)) virtually eliminated TGF-beta1-augmented PAI-1 levels...
瑾萱生物 活性重组蛋白 Human EGFR ERBB NISBD2 PIG61 mENA HER1 ￥1280.00 查看详情 生物素连接酶 Biotin Protein Ligase 生物素化标签蛋白 ￥1580.00 查看详情 瑾萱生物CRO 技术服务 Western Blot服务 WB检测 蛋白质印迹法 免疫印迹 ￥666.00 查看详情 瑾萱生物 CRO 技术服务 枯草芽孢杆菌基因编辑 CRISPR Cas9技术...
(e.g., antibodies or antigen binding regions that specifically bind thereto), EGFR inhibitory agents (e.g., antibodies or antigen binding regions that specifically bind thereto) such as panitumumab, IRESSA™ (gefitinib), TARCEVA™ (erlotinib), anti-Ang-1 and anti-Ang-2 agents (e.g., ...
TGIF2 promotes the progression of lung adenocarcinoma by bridging EGFR/RAS/ERK signaling to cancer cell stemness TGF-β-induced factor homeobox 2(TGIF2)is a transcription regulator that plays essential roles in the regulation of development and cell fate decisions.Abe... R Du,W Shen,Y Liu,....
Importantly, the effect of FGF signaling inhibition on TGFβactivity was specific. Knockdowns of epidermal growth factor receptor (EGFR), insulin-like growth factor-1 receptor (IGF1R), and platelet-derived growth factor receptor beta (PDGFRβ) had little effect on TGFβR1 protein expression or ...
瑾萱生物 活性重组蛋白 Human EGFR ERBB NISBD2 PIG61 mENA HER1 ￥1280.00 查看详情 生物素连接酶 Biotin Protein Ligase 生物素化标签蛋白 ￥1580.00 查看详情 瑾萱生物CRO 技术服务 Western Blot服务 WB检测 蛋白质印迹法 免疫印迹 ￥666.00 查看详情 瑾萱生物 CRO 技术服务 枯草芽孢杆菌基因编辑 CRISPR Cas9技术...
Terakado M, Gon Y, Sekiyama A, Takeshita I, Kozu Y, Matsumoto K, Takahashi N, Hashimoto S. The Rac1/JNK pathway is critical for EGFR-dependent barrier form... SL O'Beirne,IP Counihan,JC Barnes,... - American Thoracic Society International Conference 被引量: 1发表: 2011年 加载更多来...
CCN2;TGF-β;SMAD;TGF-β receptors;EGFR;CTGF Share and Cite MDPI and ACS Style Tejera-Muñoz, A.; Marquez-Exposito, L.; Tejedor-Santamaría, L.; Rayego-Mateos, S.; Orejudo, M.; Suarez-Álvarez, B.; López-Larrea, C.; Ruíz-Ortega, M.; Rodrigues-Díez, R.R. CCN2 Increases...