Proteins: Structure, Function, and BioinformaticsZhou H, Skolnick J. Template-based protein structure modeling using TASSERVMT. Proteins. 2011; 80(2):352-61. https://doi.org/10.1002/prot.23183 PMID: 22105797Zhou, H. and Skolnick, J. (2012) Template-based protein structure modeling using ...
A key challenge of modern biology is to uncover the functional role of the protein entities that compose cellular proteomes. To this end, the availability of reliable three-dimensional atomic models of proteins is often crucial. This protocol presents a
the availability of reliable three-dimensional atomic models of proteins is often crucial. This protocol presents a community-wide web-based method using RaptorX (http://raptorx.uchicago.edu/) for protein secondary structure prediction, template-...
The vast majority of the chores in the living cell involve protein-protein interactions. Providing details of protein interactions at the residue level and... N Tuncbag,A Gursoy,O Keskin - 《Physical Biology》 被引量: 85发表: 2011年 Template-Based Protein Structure Modeling Functional characteriza...
For template-based modeling (TBM) and fold recognition methods, a prediction model can be built based on the coordinates of the appropriate template(s) [1]. These approaches generally involve four steps: 1) a representative protein structure database is searched to identify a template that is ...
RaptorX server: A Resource for Template-Based Protein Structure Modeling Assigning functional properties to a newly discovered protein is a key challenge in modern biology. To this end, computational modeling of the three-dimens... Morten Kllberg,G Margaryan,W Sheng,... - 《Methods in Molecular...
A new approach to the prediction of protein structures that uses distance and backbone virtual-bond dihedral angle restraints derived from template-based models and simulations with the united residue (UNRES) force field is proposed. The approach combines the accuracy and reliability of template-based...
The recent growth of the number of experimentally-determined protein structures in Protein Data Banks (PDB) has provided hundreds of thousands of structural templates to support reliable template-based protein structure modeling. In this paper, taking advantage of large-scale data processing platforms, ...
Although many advanced and sophisticatedab initioapproaches for modeling protein–protein complexes have been proposed in past decades, template-based modeling (TBM) remains the most accurate and widely used approach, given a reliable template is available. However, there are many different ways to exp...
Background As the coverage of experimentally determined protein structures increases, fragment-based structural modeling approaches are expected to play an ever more important role in structural modeling. Here we introduce a structural modeling method by which an initial structural template can be extended...