Unraveling the importance of protein folding, protein鈥損rotein interaction is critical to understand cellular processes and rational drug design. A major breakthrough in protein purification technologies has greatly changed the landscape of protein study leading to a deeper understanding of their role ...
Teach foundational protein analysis techniques through real-world applications such as biofuels, immunology, endocrinology, and medical diagnostics.
The method significantly outperformed a previously proposed technique that uses the same input data.;Second, I tackled the problem of predicting the binding/functional sites in protein-ligand and enzyme-substrate interactions. These functional residues actually correspond to a protein's binding surface ...
蛋白质相互作用组学分析技术(Proteomicanalysistechniquesforproteininteractions)Inordertoexplorethemolecularmechanismsofbiologicalprocesses,protein-proteininteractionsthatmediatethisprocessneedtobeidentified.Themaintechniquesforstudyingprotein-proteininteractionsaresummarizedasfollows:YeasttwohybridsystemYeasttwohybridsystemisanimp...
New insights into therapeutic protein instability and aggregation processes by a novel analytical methodNowadays, more than 30% of newly approved drugs are proteins. A prerequisite for the application of proteins in pharmacotherapy is the ... A Hawe 被引量: 0发表: 2008年 Analysis of glycated prot...
Protein–protein interactions (PPIs) are important for the study of protein functions and pathways involved in different biological processes, as well as for understanding the cause and progression of diseases. Several high-throughput experimental techniques have been employed for the identification of PPI...
Orally administered zinc gluconate spontaneously assembles into protein-coated zinc oxide nanoparticles in human blood. These nanoparticles efficiently target renal tumours, where they enhance antitumour immune responses, and can serve as a multifunctional drug delivery system. ...
Infertility affects one in six couples worldwide, and fertility continues to deteriorate globally, partly owing to a decline in semen quality. Sperm analysis has a central role in diagnosing and treating male factor infertility. Many emerging techniques, such as digital holography, super-resolution mi...
Proteins are the building blocks of living organisms, and they play an enormous range of fundamental roles in sustaining and shaping life. The critical determinant of a protein’s function is its structure, and the analysis of protein structures has therefore become a significant component of bi...
These techniques comprise direct detection of mutations (including trinucleotide repeats) and linkage analysis. The usefulness of these techniques is compared to conventional biochemical tests for the diagnosis of various . The authors stress the need for caution in the interpretation of test results and...