T cell receptor (TcR) beta chain transgenic mice: studies on allelic exclusion and on the TcR+ gamma/delta population. Eur J Immunol. 1990 Feb; 20 (2):417–424.Pircher, H., Ohashi, P., Miescher, G., Lang, R., Zikopoulos, A., Burki, K., Mak, T. W., MacDonald, H. R., ...
Nonobese diabetic (NOD) mice spontaneously develop a disease very similar to type 1 diabetes in humans. We have generated a transgenic mouse strain carryin... JD Katz,W Bo,K Haskins,... - 《Cell》 被引量: 1393发表: 1993年 Initiation of Autoimmune Diabetes by Developmentally Regulated Presen...
TCR transgenic regulatory T cells prevent lethal graft-versus-host disease 来自 国家科技图书文献中心 喜欢 0 阅读量: 38 作者:Y Sorge,P Ostermann,B Bayer,J Klempnauer,M W Hoffmann 摘要: The beneficial effect of deoxyspergualin (DSG, NKT-01) on lethal graft-versus-host disease in mice has...
Naive CD8+ T cells were purified by negative selection from spleens of 2C transgenic mice housed in the animal facility of Emory University following a protocol approved by the Institute Animal Care and Use Committee of Emory University as described2. Briefly, C57BL/6J mice (Jackson Laboratories...
Differing from other TCR trials, patients did not receive lymphodepletion or IL-2 Colorectal cancer (CRC) CEA is an antigen often highly expressed in metastatic CRC. Parkhurst et al. developed a TCR, where the peptide epitope CEA:691–699 was administered in HLA-A*0201 transgenic mice, ...
We have previously reported that a subset of T cells in T cell receptor (TCR)-transgenic mice may express two different chains on their surface. The expre... WR Heath,FR Carbone,P Bertolino,... - 《European Journal of Immunology》 被引量: 340发表: 1995年 Engagement of the T-cell rece...
In this model, the transgenic Tcr recognizes residues 91 - 101 of a lambda2(315) Ig light chain, presented on the I-Ed class II molecule. From such mice, a CD4+ T cell clone was isolated which not only responded to lambda2(315), but also mobilized Ca2+ and proliferated in response ...
• Detection of T cells in the thymus ofTraKO mice Figure 1. Detection of T cells in the thymus ofTraKO mice • Detection of T cells in blood and spleen ofTraKO mice Figure 2. Detection of T cells in blood and spleen ofTraKO mice ...
Transgenic mice expressing functional CD8αβ without an active CD8αα implies the contribution of CD8αα in the biological function of CD8αα+TCRαβ+ iIELs (P1466)To understand the functional significance of CD8αα complexes in ... Kang,YoonJoong,Chang,... 被引量: 0发表: 0年 Select...
Mountz JD, Zhou T, Bluethmann H, Wu J, Edwards CK. Apoptosis defects analyzed in TcR transgenic and Fas transgenic lpr mice. Int Rev Immunol 1994; 11: 321-342.Mountz, J. D., T. Zhou, H. Bluethmann, J. Wu, and C. R. Edwards. 1994. Apoptosis defects analyzed in TcR transgenic...